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Why and How Your Body Makes Millions of Red Blood Cells Every Minute

In this activity, students learn about stem cells, cell differentiation, and how transcription factors contribute to cell differentiation. These concepts are introduced as students learn how the body makes red blood cells and answer multiple minds-on questions.

The Student Handout is available in the first two attached files and as a Google doc, designed for use in online instruction and distance learning. (For additional instructions, see, especially item 7.) The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards.

red blood cells SHO.docx6.7 MB
red blood cells SHO.pdf322.23 KB
red blood cells TN.docx731.65 KB
red blood cells TN.pdf466.6 KB


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