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A mistake in copying DNA can result in dwarfism.
In this minds-on activity, students analyze evidence about achondroplasia to learn how a mistake in DNA replication can result in a new mutation that affects a child’s characteristics.
This analysis and discussion activity reviews several basic genetics principles and helps to counteract several common misconceptions about genetics.
The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards.
Attachment | Size |
---|---|
dwarfism SH.docx | 1.46 MB |
dwarfism SH.pdf | 304.71 KB |
dwarfism TN.docx | 42.89 KB |
dwarfism TN.pdf | 244.15 KB |
Download Minds-On Activities for Teaching Biology
Introduction and Activities Listing
Intro and Biological Molecules
- Characteristics of Life
- Levels of Organization in Biology (NGSS)
- Introduction to Proteins and DNA (NGSS)
- Enzymes Help Us Digest Food (NGSS; hands-on)
- A Scientific Investigation – What types of food contain starch and protein? (NGSS; hands-on)
- Coronaviruses – Introduction (NGSS)
- Who Took Jerell’s iPod? -- An Organic Compound Mystery (hands-on)
- Is Yeast Alive? (hands-on)
- Macromolecules Jeopardy
Cell Structure and Function
- Cell Structure and Function – Major Concepts and Learning Activities
- Cells – How do they carry out the activities of life? (NGSS)
- Why do some plants grow in odd shapes? (NGSS)
- Introduction to Osmosis (NGSS; hands-on)
- Cell Membrane Structure and Function (NGSS; hands-on)
- Cell Vocabulary Review Game
Cellular Respiration and Photosynthesis
- Cellular Respiration and Photosynthesis - Key Concepts and Activities
- How do organisms use energy? (NGSS)
- Using Models to Understand Cellular Respiration (NGSS)
- Using Models to Understand Photosynthesis (NGSS)
- Photosynthesis, Cellular Respiration and Plant Growth (NGSS; hands-on)
- Food, Physical Activity, and Body Weight (NGSS)
- How do muscles get the energy they need for athletic activity? (NGSS)
- Alcoholic Fermentation in Yeast – A Bioengineering Design Challenge (NGSS; hands-on)
- Plant Growth Puzzle (NGSS)
- Where does a tree’s mass come from? (NGSS)
- Photosynthesis Investigation (NGSS; hands-on)
Cell Division
- Mitosis and the Cell Cycle (NGSS; hands-on)
- Mitosis and the Cell Cycle (NGSS)
- Meiosis and Fertilization – Understanding How Genes Are Inherited (NGSS; hands-on)
- Understanding How Genes are Inherited via Meiosis and Fertilization (NGSS)
- Comparing Mitosis and Meiosis
- What causes melanoma and other types of cancer? (NGSS)
- Mistakes in Meiosis – Down Syndrome or Embryo Death (NGSS)
- Mitosis, Meiosis and Fertilization Vocabulary Review Game
Genetics
- Genetics Concepts and Activities (NGSS)
- Genetics (NGSS; hands-on)
- Genetics Intro – Family Members (NGSS)
- Genetics Sickle Cell Anemia and Trait (NGSS)
- Genetics Probability – Sex Ratios (NGSS)
- Mistake in copying DNA & Dwarfism (NGSS)
- Soap Opera Genetics (NGSS)
- Were the babies switched? The Genetics of Blood Types (NGSS; hands-on)
- Dragon Genetics I (hands-on)
- Dragon Genetics II (hands-on)
- Learning about Genetic Disorders
- Genetics Vocabulary Review Game
- Genetics Jeopardy
Molecular Biology
- Molecular Biology: Major Concepts and Learning Activities (NGSS)
- DNA (NGSS; hands-on)
- DNA Function, Structure and Replication (NGSS)
- How Genes Can Cause Disease - Introduction to Transcription and Translation (NGSS; hands-on)
- How Genes Can Cause Disease - Understanding Transcription and Translation (NGSS)
- UV, Mutations and DNA Repair (NGSS; hands-on)
- What types of mutations cause more vs. less severe muscular dystrophy? (NGSS)
- Making Red Blood Cells (NGSS)
- Genetic Engineering Challenge – Preventing Vitamin A Deficiency (NGSS)
- Gene Editing with CRISPR-Cas – Potential Sickle Cell Anemia Cure (NGSS)
- Molecular Biology Vocabulary Review Game
Evolution
- Resources for Teaching and Learning about Evolution
- Evolution by Natural Selection (NGSS; hands-on)
- What is natural selection? (NGSS)
- Natural Selection and the Peppered Moth (NGSS)
- How have mutations and natural selection affected fur color in mice? (NGSS)
- How Whales Evolved (NGSS)
- How Eyes Evolved – Analyzing the Evidence (NGSS)
- How does evolution result in similarities and differences? (NGSS; hands-on)
- What is a species? (NGSS)
- Coronavirus Evolution and the COVID-19 Pandemic (NGSS)
- Evolution and Adaptations (NGSS)
Ecology
- Ecology Concepts and Learning Activities (NGSS)
- Exponential and Logistic Population Growth Models vs. Complex Reality (NGSS)
- Some Similarities between the Spread of Infectious Disease and Population Growth (NGSS; hands-on)
- Stability and Change in Biological Communities (NGSS)
- Food Webs, Energy Flow, Carbon Cycle and Trophic Pyramids (NGSS)
- Food Webs (NGSS)
- Carbon Cycles and Energy Flow through Ecosystems (NGSS)
- Trophic Pyramids (NGSS)
- Introduction to Global Warming (NGSS)
- Food and Climate Change – How can we feed a growing world population without increasing global warming? (NGSS)
- Coral Bleaching (NGSS)
- Global Warming (NGSS) (NGSS)
- Resources for Teaching about Climate Change
- The Ecology of Lyme Disease (NGSS)
Human Physiology and Health
- Negative Feedback, Homeostasis, and Positive Feedback, with Breathing Experiment (NGSS; hands-on)
- Homeostasis, Negative Feedback, and Positive Feedback (NGSS)
- How do food molecules reach our muscles? (NGSS)
- How do we Sense the Flavors of Food? (NGSS; hands-on)
- COVID-19 Vaccines (NGSS)
- Molecular and Evolutionary Biology of HIV/AIDS and Treatment (NGSS)
- Resources for Teaching Cancer Biology
- Carbohydrate Consumption, Athletics, Health – Using Science Process Skills
- Vitamins and Health – Why Experts Disagree
- Regulation of Human Heart Rate (hands-on)
- Should You Drink Sports Drinks? When? Why?
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Comments
2023 revision
The revised Student Handout begins with the driving question and a photo of the anchoring phenomenon. The expanded Student Handout has additional questions about the genetics of achondroplasia.
Ingrid
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