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cell biology

Why do some plants grow in odd shapes?

In this analysis and discussion activity, students investigate several examples of plants that have grown in odd shapes.

As students analyze these phenomena, they learn (1) how the zones of cell division and elongation contribute to the growth of stems and roots; (2) how the effects of a plant hormone on cell elongation contribute to plant responses to light and gravity; and (3) how differentiated cells (xylem cells, phloem cells and photosynthetic cells) cooperate to supply all parts of the plant with needed molecules and ions.

In this activity, students interpret data from scientific studies, develop and refine scientific models, and answer additional analysis and discussion questions.

Melanoma, Mutations and Abnormal Cell Cycles

This minds-on, analysis and discussion activity introduces students to basic cancer biology, somatic mutations, and regulation of the cell cycle. After students view an introductory video about a teen with melanoma, they complete five sections: “What is melanoma?”, “How does a melanoma develop?”, “Why do melanoma cells divide too much?”, “Genes, Environment and Melanoma”, and a final section in which students summarize their major conclusions about melanoma and learn which of these conclusions generalize to other types of cancer.

Mitosis and the Cell Cycle – How the Trillions of Cells in a Human Body Developed from a Single Cell

In this minds-on analysis and discussion activity, students learn how the cell cycle produces genetically identical daughter cells. They analyze how DNA replication and mitosis work together to ensure that each new cell gets a complete set of chromosomes with a complete set of genes.

To understand how a single cell (the fertilized egg) can develop into the trillions of cells in a human body, students analyze an exponential growth model for the increase in number of cells. The final section provides a brief introduction to cellular differentiation.

This activity can be used as an introduction to mitosis or to reinforce understanding of mitosis. A hands-on version of this activity is available as “Mitosis and the Cell Cycle – How a Single Cell Develops into the Trillions of Cells in a Human Body”.

Comparing Mitosis and Meiosis

In this minds-on analysis and discussion activity, students review mitosis and meiosis as they compare and contrast these two types of cell division. The Teacher Notes for this activity include an optional mitosis and meiosis card sort for additional review.

The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information.

Introduction to Cells

Organelles in animal and plant cellsIn this minds-on analysis and discussion activity, students learn about the characteristics shared by all cells, the differences between prokaryotic and eukaryotic cells, and the differences between animal and plant cells.

Students analyze the reasons why cells are so small. They also learn about the diverse chemical capabilities of prokaryotes, the functions of the organelles in eukaryotic cells, and how organelles work together to accomplish the activities of life.     

Using Models to Understand Cellular Respiration

To begin, students analyze two models of cellular respiration – chemical equations that summarize the inputs and outputs of cellular respiration and a figure that summarizes the three major stages of cellular respiration (glycolysis, the Krebs cycle, and the electron transport chain plus ATP synthase).

Then, students use what they have learned to develop their own model of cellular respiration.

In the optional final section, students analyze how the extensive, folded inner membrane of a mitochondrion contributes to ATP production. This illustrates the general principle that structure is related to function.

Cell Differentiation and Epigenetics

Red blood cells and skin cellsIn this analysis and discussion activity, students answer minds-on questions as they learn about the differentiation of specialized cell types, including the role of changes in epigenetic control of gene expression during cell differentiation.

Students also learn about environmental influences on epigenetic control of gene expression and the need for cell division and differentiation even in a fully grown adult.

The Student Handout is available in the first two attached files and as a Google doc, designed for use in online instruction and distance learning. (For additional instructions, see https://serendipstudio.org/exchange/bioactivities/Googledocs, especially item 7.) The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards.

Structure and Function of Cells, Organs and Organ Systems

Process of phagocytosis after injury to skinIn this activity, students analyze multiple examples of the relationship between structure and function in diverse human cells and in the digestive system.

Students learn that cells are dynamic, with constant molecular activity.

Students analyze examples that illustrate how organelles work together to accomplish cellular functions and organs and organ systems work together to accomplish functions needed by the organism.

Finally, students evaluate the claim that structure is related to function in cells, organs and organ systems.

Resources for Teaching Cancer Biology

These Teacher Notes describe multiple learning activities that introduce students to varied aspects of cancer biology. These Teacher Notes also describe multiple sources of reliable information about cancer and provide suggestions about how to convert information sources to learning activities.

Cell Structure and Function – Major Concepts and Learning Activities

These Teacher Notes present key concepts and suggest learning activities that engage students in active learning and counteract some common student misconceptions. Students often think of a cell as a static structure consisting of multiple independent parts. They often do not understand how the parts of the cell work together to accomplish the multiple functions of a dynamic living cell. All of the suggested learning activities will help students to meet the Next Generation Science Standards (NGSS).

Section I presents key concepts and learning activities concerning cell structure and function, including differences between prokaryotic and eukaryotic cells and different types of eukaryotic cells. Section II presents key concepts and learning activities concerning the structure and function of cell membranes. The cell membrane is a particularly clear example of how the structure and function of a cell part can be understood in terms of the types and organization of its component molecules. The structure and function of mitochondria and chloroplasts are discussed further in the overview of cellular respiration and photosynthesis (https://serendipstudio.org/exchange/bioactivities#energy). Nucleus and ribosome function is discussed further in the overview of molecular biology (https://serendipstudio.org/exchange/bioactivities#molecbio).

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