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mitosis

What causes melanoma and other types of cancer?

This minds-on, analysis and discussion activity introduces students to basic cancer biology, somatic mutations, and regulation of the cell cycle.

Students view an introductory video about a teen with melanoma and then complete six sections: “What is melanoma?”, “How does a melanoma develop?”, “Why do melanoma cells divide too much?”, “Environment and inherited genes influence your risk of melanoma.”, “Different Types of Cancer”, and “Research Challenge”.

Concepts covered include cell cycle checkpoints, somatic mutations, and DNA repair enzymes

Mitosis and the Cell Cycle – How the Trillions of Cells in a Human Body Developed from a Single Cell

In this minds-on analysis and discussion activity, students learn how the cell cycle produces genetically identical daughter cells. They analyze how DNA replication and mitosis work together to ensure that each new cell gets a complete set of chromosomes with a complete set of genes.

To understand how a single cell (the fertilized egg) can develop into the trillions of cells in a human body, students analyze an exponential growth model for the increase in number of cells. The final section provides a brief introduction to cellular differentiation.

This activity can be used as an introduction to mitosis or to reinforce understanding of mitosis. A hands-on version of this activity is available as “Mitosis and the Cell Cycle – How a Single Cell Develops into the Trillions of Cells in a Human Body”.

Comparing Mitosis and Meiosis

In this minds-on analysis and discussion activity, students review mitosis and meiosis as they compare and contrast these two types of cell division. The Teacher Notes for this activity include an optional mitosis and meiosis card sort for additional review.

The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information.

Mitosis and the Cell Cycle - How a Single Cell Develops into the Trillions of Cells in a Human Body

Cell cycle producing daughter cellsIn this hands-on, minds-on activity, students use model chromosomes and answer analysis and discussion questions to learn how the cell cycle produces genetically identical daughter cells.

Students learn how DNA replication and mitosis ensure that each new cell gets a complete set of chromosomes with a complete set of genes.Students learn why each cell needs a complete set of genes and how genes influence phenotypic characteristics.

To understand how a single cell (the fertilized egg) develops into the trillions of cells in a human body, students analyze an exponential growth model of increase in number of cells. The final section provides a very brief introduction to cellular differentiation. 

This activity can be used as an introduction to mitosis or to reinforce understanding of mitosis. 

In our follow-up meiosis and fertilization activity (/sci_edu/waldron/#meiosis) students learn how the movement of gene-carrying chromosomes during meiosis and fertilization results in the inheritance of genes.

Resources for Teaching Cancer Biology

These Teacher Notes describe multiple learning activities that introduce students to varied aspects of cancer biology. These Teacher Notes also describe multiple sources of reliable information about cancer and provide suggestions about how to convert information sources to learning activities.

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