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Coronaviruses – What They Are and How They Can Make You Sick

Cross section of Coronavirus

In the shorter version of the Student Handout, students learn how coronaviruses are replicated inside our cells, how white blood cells fight a coronavirus infection, and how a coronavirus infection can cause you to feel sick.

In the longer version of the Student Handout, students also learn how the respiratory and circulatory systems work together to provide oxygen to the body’s cells, and they learn how a coronavirus infection can interfere with oxygen delivery, which can result in severe disease.

How Genes Can Cause Disease – Understanding Transcription and Translation

Transcription with RNA nucleotides

In the first section of this analysis and discussion activity, students learn that different versions of a gene give the instructions for making different versions of a clotting protein, which result in normal blood clotting or hemophilia.

Next, students learn how genes provide the instructions for making a protein via the processes of transcription and translation. They develop an understanding of the roles of RNA polymerase, the base-pairing rules, mRNA, tRNA and ribosomes.

Finally, students use their learning about transcription and translation to understand how a change in a single nucleotide in the hemoglobin gene can result in sickle cell anemia.

Throughout this activity, students use the information in brief explanations, figures and videos to answer analysis and discussion questions.

This activity can be used to introduce students to transcription and translation or to reinforce and enhance student understanding. 

If you prefer a hands-on activity that uses simple paper models to simulate the molecular processes of transcription and translation, see “How Genes Can Cause Disease – Introduction to Transcription and Translation” (http://serendipstudio.org/sci_edu/waldron/#trans).

A Scientific Investigation – What types of food contain starch and protein?

Starch molecule

In the first part of this activity, students use basic information about the structure, functions, and synthesis of starch and proteins to understand why certain parts of plants or animals contain starch and/or proteins.

Then, students practice the scientific method by carrying out key components of a scientific investigation, including generating hypotheses, developing experimental methods, designing and carrying out experiments to test their hypotheses, and, if needed, using experimental results to revise their hypotheses. (NGSS)

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

Enzymes Help Us Digest Food

In this hands-on, minds-on activity, students investigate the biological causes of Maria’s symptoms and Jayden’s symptoms. To explore the causes of these symptoms, students carry out two experiments and interpret the results, and they answer additional analysis and discussion questions.

Students learn about enzyme function and enzyme specificity as they figure out that Maria’s symptoms are due to lactase deficiency (resulting in lactose intolerance) and Jayden’s symptoms are due to sucrase deficiency.

In the final section, students are challenged to generalize their understanding of enzymes to interpret a video of an experiment with saliva, starch and iodine. This activity can be used in an introductory unit on biological molecules or later during a discussion of enzymes.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

Introduction to Proteins and DNA

The Teacher Notes present a sequence of activities that will help students understand the basic structure and function of proteins and DNA.

To understand how genes influence our characteristics, students learn that different versions of a protein can result in different characteristics, and a gene in the DNA determines which version of a protein is synthesized by a person’s cells.

This information is conveyed through a PowerPoint with a sequence of discussion questions and videos, a Student Handout, and an optional hands-on learning activity. This sequence can be used in an introductory unit on biological molecules or to introduce a unit on molecular biology.

How Genes Can Cause Disease - Introduction to Transcription and Translation

Process of transcription and translation

To begin this hands-on, minds-on activity, students learn that different versions of a gene give the instructions for making different versions of a clotting protein, which result in normal blood clotting or hemophilia.

Then, students learn how genes provide the instructions for making a protein via the processes of transcription and translation. They develop an understanding of the roles of RNA polymerase, the base-pairing rules, mRNA, tRNA and ribosomes.

Finally, students use their learning about transcription and translation to understand how a change in a single nucleotide in the hemoglobin gene can result in sickle cell anemia.

Throughout, students use the information in brief explanations, figures and videos to answer analysis and discussion questions. In addition, students use simple paper models to simulate the processes of transcription and translation.

An alternative version omits the paper models (How Genes Can Cause Disease – Understanding Transcription and Translation).

Download Student Handout: PDF format or Word format

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