This minds-on, hands-on activity begins with an anchoring phenomenon, how a person’s breathing changes when he/she is re-breathing the air in a plastic bag. Students develop a negative feedback model of how the changes in breathing stabilize blood levels of O2 and CO2.
Then, students use a negative feedback model to understand temperature regulation, homeostasis, and how a change in setpoint can result in a fever.
Next, students analyze how failures of negative feedback regulation of blood glucose levels can result in diabetes.
Finally, students compare and contrast positive and negative feedback. Throughout this activity, students learn relevant human physiology.
An Appendix for the Teacher Preparation Notes suggests an optional activity in which each student group investigates a question or hypothesis concerning negative feedback, homeostasis and changes in breathing.
Download Student Handout: PDF format or Word format