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activities for teaching biology

What types of mutations cause more vs. less severe muscular dystrophy?

This analysis and discussion activity begins with a brief video presenting the anchoring phenomenon – a teenager who has Duchenne muscular dystrophy.

Then, students investigate the types of deletion mutation that cause the more severe Duchenne muscular dystrophy vs. the milder Becker muscular dystrophy. During this analysis, students review transcription and translation, learn how to use a codon wheel, and analyze the molecular effects of different types of deletion and point mutations.

Finally, students investigate X-linked recessive mutations to understand why almost all Duchenne muscular dystrophy patients are male.

The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. (For additional instructions, see https://serendipstudio.org/exchange/bioactivities/Googledocs, especially item 7.) The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards (NGSS).

DNA Function, Structure and Replication

DNA structure

In this analysis and discussion activity, students learn that the sequence of nucleotides in a gene in DNA determines the sequence of amino acids in a protein, which determines the structure and function of the protein. Different versions of a gene give the instructions to make different versions of a protein, which can result in different characteristics.

Since many different proteins are needed for a cell to be alive, each cell needs a complete copy of the DNA with all of the genes. Therefore, before a cell divides, it needs to make a copy of all its DNA. Students analyze DNA replication to understand how the double helix structure of DNA and the base-pairing rules work together to produce two identical copies of the original DNA molecule.

The Student Handout is available in the first two attached files. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards (NGSS). 

Molecular Biology Vocabulary Review Game

This game helps students to enjoy reviewing vocabulary related to molecular biology, including DNA and RNA structure and function, transcription and translation. Each card in the deck has a target vocabulary word and two related taboo words that the student may not use as he/she gives clues so the other students in his/her small group can guess the target word. Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms. 

The first file below provides the master copy for creating the card decks for this game, and the second file below provides the teacher notes, including instructions for playing the game. 

Cell Structure and Function – Major Concepts and Learning Activities

These Teacher Notes present key concepts and suggest learning activities that engage students in active learning and counteract some common student misconceptions. Students often think of a cell as a static structure consisting of multiple independent parts. They often do not understand how the parts of the cell work together to accomplish the multiple functions of a dynamic living cell. All of the suggested learning activities will help students to meet the Next Generation Science Standards (NGSS).

Section I presents key concepts and learning activities concerning cell structure and function, including differences between prokaryotic and eukaryotic cells and different types of eukaryotic cells. Section II presents key concepts and learning activities concerning the structure and function of cell membranes. The cell membrane is a particularly clear example of how the structure and function of a cell part can be understood in terms of the types and organization of its component molecules. The structure and function of mitochondria and chloroplasts are discussed further in the overview of cellular respiration and photosynthesis (https://serendipstudio.org/exchange/bioactivities#energy). Nucleus and ribosome function is discussed further in the overview of molecular biology (https://serendipstudio.org/exchange/bioactivities#molecbio).

Diffusion and Cell Size and Shape

This analysis and discussion activity helps students understand that cell size is limited by the very slow rate of diffusion over any substantial distance and the insufficient surface-area-to-volume ratio for larger cells.  In addition, students calculate why these problems do not apply to long slender cells or parts of cells (e.g. the axons of neurons that extend from your spinal cord to your foot).

The first attached file has the Student Handout and the second attached file has the Teacher Notes.

Cell Vocabulary Review Game

This game helps students to enjoy reviewing vocabulary related to cells, organelles, and the plasma membrane.  Each card in the deck has a target vocabulary word and two related taboo words that the student may not use as he/she gives clues so the other students in his/her small group can guess the target word.  Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms. 

The first file below provides the master copy for creating the card decks for this game, and the second file below provides the teacher notes, including instructions for playing the game.

How do organisms use energy?

Enzymes convert substrates to product

This analysis and discussion activity introduces students to the basic principles of how organisms use energy.

Students learn that, in cellular respiration, glucose is one input for reactions that provide the energy to make ATP. The hydrolysis of ATP provides the energy for many cellular processes.

Students apply the principles of conservation of energy and conservation of matter to avoid common errors and correct common misconceptions.

The Student Handout is available in the first two attached files and as a Google doc designed for use in distance learning and online instruction. The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards.

Genetics Review Game

This game (in the style of the Jeopardy TV show) reviews genetics, with 25 questions of varying levels of difficulty. The PowerPoint has the questions. Two ways of organizing the Jeopardy game are recommended in the Teacher Notes available in the second attachment below.

Genetics Vocabulary Review Game

This game helps students to enjoy reviewing vocabulary related to genetics.  Each card in the deck has a target vocabulary word and two related taboo words that the student may not use as he/she gives clues so the other students in his/her small group can guess the target word.  Many students have trouble learning the substantial new vocabulary required for biology, and this game lets students have fun while reinforcing their understanding of key terms. 

The first file below provides the master copy for creating the card decks for this game, and the second file below provides the teacher notes, including instructions for playing the game.

 

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