To begin this minds-on analysis and discussion activity, students learn about the correlated increases in global temperatures and CO₂ concentrations in the atmosphere.

Next, students evaluate an example that illustrates that correlation does not necessarily imply causation. Then, they analyze several types of evidence to test the hypothesis that increased CO₂ in the atmosphere has been a major cause of the increase in global temperatures.

This activity concludes with a very brief discussion of how global warming has contributed to harmful effects (e.g., increased flooding) and possible actions to reduce these harmful effects.

This analysis and discussion activity introduces Victoria Gray whose severe sickle cell anemia was effectively treated by gene editing with CRISPR-Cas.

To begin, students review the molecular biology of sickle cell anemia, transcription and translation.

Next, they learn how bacteria use CRISPR-Cas to defend against viral infections. Then, students examine some of the research findings that scientists used to identify the target for gene editing.

Finally, students analyze the CRISPR-Cas gene editing treatment for sickle cell anemia.

The Teacher Notes present an optional additional video and question to stimulate students to consider the ethical controversies related to potential uses of CRISPR-Cas.

Students learn that vaccination or a previous coronavirus infection reduces the risk of severe Covid-19.

They learn how the immune system responds to a coronavirus infection and analyze how this response differs after a first vs. second exposure to the coronavirus.

Then, students analyze the biological effects of an mRNA vaccine and develop an evidence-based explanation of how vaccination protects against severe Covid-19.

ARCHIVED PAGE
Please see: this Teaching Resources page for current information.

Our understanding of the novel coronavirus and the COVID-19 pandemic continues to change rapidly. The following resources for teaching high school biology students are up-to-date as of mid-November, 2020.¹ On this page:

In this activity, students analyze information about the molecular and cellular basis for sickle cell anemia and sickle cell trait. This provides the basis for understanding how a single gene can affect multiple phenotypic characteristics.

Students also create a Punnett square, analyze a pedigree, and evaluate the relative advantages of Punnett squares and pedigrees as models of inheritance.

The Teacher Notes include several optional questions which apply student understanding of the biology of sickle cell trait to practical and policy issues.

In this minds-on analysis and discussion activity, students analyze the inheritance of sex chromosomes. Students use a Punnett square to predict the sex ratio of births and compare their prediction to data for individual families and for the entire US.

As students analyze the reasons why many real families deviate from Punnett square predictions, they learn about the probabilistic nature of inheritance and the limitations of Punnett square predictions.

In this minds-on activity, students analyze evidence about achondroplasia to learn how a mistake in DNA replication can result in a new mutation that affects a child’s characteristics.

This analysis and discussion activity reviews several basic genetics principles and helps to counteract several common misconceptions about genetics.

To begin this activity, students propose a hypothesis about how genes contribute to the similarities and differences in appearance of family members. Students repeatedly refine their hypothesis as they learn more.

Students learn that different versions of a gene give the instructions for making different versions of a protein which can result in different characteristics. Next, students review how genes are transmitted from parents to offspring through the processes of meiosis and fertilization. Then, students analyze several examples that illustrate how inheritance of genes can result in family resemblance and/or differences.

Concepts covered include Punnett squares, dominant and recessive alleles, incomplete dominance, and polygenic inheritance.

University of Pennsylvania biologists Ingrid Waldron and Lori Spindler offer free professional development workshops for high school biology teachers and middle school life science teachers. They have recorded this workshop about Energy Metabolism.

Links to the materials:

• How do organisms use energy?
• Using Models to Understand Cellular Respiration
• How do muscles get the energy they need for athletic activity?
• Food, Energy and Body Weight

Recorded October 24, 2020

 In this minds-on activity, students answer analysis and discussion questions to learn how a child inherits one copy of each gene from each parent via the processes of meiosis and fertilization. They analyze how the processes of meiosis and fertilization result in the alternation between diploid and haploid cells in the human lifecycle.

To learn how meiosis produces genetically diverse gametes, students analyze the results of crossing over and independent assortment.

Then, students follow the alleles of a human gene from the parents' body cells through gametes and zygote to a child’s cells. They learn how the outcomes of meiosis and fertilization can be represented in a Punnett square.

A brief final section contrasts sexual reproduction with asexual reproduction. 

This activity can be used to introduce meiosis and fertilization or to review these processes. A hands-on version of this activity is available as “Meiosis and Fertilization – Understanding How Genes Are Inherited”.