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The Effects of Hallucinogenic Drugs on The Brain

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Biology 202
1998 First Web Reports
On Serendip

The Effects of Hallucinogenic Drugs on The Brain

Alicia Ebbitt

Hallucinnogenic Drugs alter a person's perceptions of reality and may cause hallucinations and other alterations of the senses. Drugs classified as hallucinogens include: LSD (lysergic acid diethylamide), 2,5-dimethoxy-4-methylamphetime(DOM), N,N-dimethyltrptamine(DMT), psilocin, and mescaline. There are two aspects of these drugs that classify then as hallucinogens. They all have common side effects, including distortion of sensory perception, and other psychic and somatic effects. These drugs also exhibit cross-tolerance. This means that a user of hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used and the shorter the time span is between the last usage.

Hallucinogenic drugs have been used throughout history for a number of reasons. They have been used as medicinal agents as well as having served religious purposes. Hallucinogens such as mescaline have been used in Native American ritual ceremonies. There was extensive usage of hallucinogens in the 60's and 70's as part of the counter- culture hippie movement. During the "acid tests" of this era, hallucinogenic drugs were used for mind exploration (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinogenic drugs cause both physical and psychological effects on humans. The physical effects of these drugs include: dilated pupils, elevated body temperature, increased heart rate and blood pressure, appetite loss, sleeplessness, tremors, headaches, nausea, sweating, heart palpitations, blurring of vision, memory loss, trembling, and itching. A user of hallucinogenic drugs will also experience a number of psychological alterations in the brain. These drugs may cause hallucinations and illusions as well, as the amplification of sense, and the alterations of thinking and self-awareness. It is quite possible to have a bad reaction to hallucinogenic drugs. This is referred to as a "bad trip" and may cause panic, confusion, suspicion, anxiety, and loss of control. The long-term effects of these drugs can be quite dangerous. These long-term effects may include: flashbacks, mood swings, impaired thinking, unexpected outbursts of violence and eventually possibly depression that may lead to death or suicide.

Quite a lot of interest concerning hallucinogens has been generated by neurobiologists and other scientists. The effects that hallucinogenic drugs have on the brain are quite complicated and very interesting. Many users of hallucinogenic drugs have experienced whole personality changes which raises questions about the relationship between brain and behavior. Scientists are also curious as to how total alterations of the senses can occur as the result of hallucinogen usage. Many people that have used hallucinogens claim to have "seen sounds" or "heard colors". Scientists ask questions such as: How can a person under the influence of hallucinogenic drugs see things that aren't there? or How do flashbacks work? Another aspect of hallucinogenic drugs that interests scientists is that they are psychomimetic meaning that they mimic certain aspects of psychosis. Through the use of hallucinogenic drugs, one can induce temporary symptoms of psychosis.

As a result of the great interest in hallucinogens, many years of research have been done to try and determine exactly how the brain is affected by these drugs. Scientists have tried to determine if there is a specific site in the brain where hallucinogens act. This has been difficult to determine. Scientists still are unable to answer all questions about hallucinogenic drugs. However they have been able to determine certain areas of the brain that these drugs do act upon.

Early on in the reasearch on hallucinogens, it was determined that hallucinogenic drugs structurally resemble serotonin (5-HT) Serotonin is found in specific neurons in the brain that mediate chemical neurotransmission in the brain. Neurons containing serotonin can be found in the brain stem section of the brain. Axons of serotonergic neurons project to almost every part of the brain, affecting and communicating with all sections of the brain. Serotonin also acts at many receptor areas of neurons. Because hallucinogenic drugs are structurally similar to serotonin, it was theorized that hallucinogenic drugs may act upon serotonergic neurons (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Scientists began to carefully study the serotonin system and found out that hallucinogens do in fact have some kind of effect on serotonin. Hallucinogenic drugs cause an increase in the level of brain serotonin, but they inhibit the rapid firing of neurons containing serotonin. This is a negative feedback system in which as the serotonin level rises, the activity of serotonergic neurons decreases. It was originally theorized that this effect of hallucinogenic drugs directly caused sense alteration and hallucinations. Several observations however have shown this theory not to be true. These observations include the following: Low doses of LSD effect behavior, but do not depress firing of serotonergic neurons, The behavioral effects of LSD outlast the alteration of the firing of the serotonergic neurons, Repeated dosage of LSD results in a decrease of behavioral changes, but still effects neuron firing, Other hallucinogens do not affect serotonergic neurons, When serotonin levels are depleted, the effectiveness of LSD is not eliminated (Ian Leicht, "Postulated Mechanisms of LSD").

It has now been determined that the effects of hallucinogenic drugs are actually caused by the effects that hallucinogenic drugs have on the post-synaptic activity of serotonergic neurons. Hallucinogenic drugs directly affect the serotonin receptors(specifically the serotonin receptor subtype, 5-HT2), which is what eventually results in a complex pattern of action potentials and activity. This was proven by the fact that the depletion of serotonin levels in animals does not result in a decrease of behavioral effects caused by hallucinogenic drugs (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinations and other effects of hallucinogens are however very complicated experiences. They are not simply a part of a cause and effect system in the brain, where hallucinogenic drugs act on serotonin and cause hallucinations. Instead, hallucinogenic drugs act initially on the serotonin system, which sends into motion, a pattern of complex action potentials and activity. Other neurotransmitters may be involved in these activities as well. The effects that inputs and outputs have on each other in this system as well as the pattern of action potentials mediated by hallucinogenic drugs help to cause many of the complex changes that allow hallucinations to happen. (B.L. Jacobs, "How Hallucinogenic Drugs Work") Scientists continue to do research to determine the exact effects that hallucinogens have on the serotonin receptors and to answer any questions that they cannot yet answer.


WWW Sources

1) NIDA (National Institution Drug Abuse: LSD(Lysergic Acid Diethylamide).

2) Hallucinogenic Drugs in Psychiatric Research and Treatment: Perspectives and Prospects.

3) Tryptamine Hallucinogens and Consciousness.

4) Hallucinogens (PCP, LSD, etc.).

5) Narcotics, Dangerous Drugs, and Marijuana.

6) Healthguide Online: Substance Abuse: Hallucinogens.

7) Hallucinogens.

8) Los Angeles Police Department Drug Recognition Expert Unit: Hallucinogens.

9) Postulated Mechanisms of LSD.

10) B.L. Jacobs. 1987. How Hallucinogenic Drugs Work. "American Scientist". 75:385-92.

11) M.C. Bindal, S.P. Gupta, and P. Singh. 1983. QSAR Studies on Hallucinogens. "Chemical Reviews". 83:633-49.


Comments made prior to 2007

When you list the drugs in the beginning of your article you list lsd psilocin and mescaline. But "psilocin" is not actually the active ingredient in hallucinogenic mushrooms. The correct term is "Psilocybin". Just thought I'd point that out ... Daniel, 19 February 2007


rdanfort's picture

I don't mean to diminish your horrible experience

...but you're using a particularly rare, if widely feared outcome of the use of a relatively uncommon class of drugs to drum up a moral panic.  There's something sort of amazing about a "bad trip" in a hospital being invoked as the epitome of drug-related social decay.  Drive ten miles outside of your suburb, and you will see far worse happening to far more for far longer, without a hospital in sight.

What happened to your daughter is not "the true effect of what a society with drugs in schools is doing to our children."  It is a much better representation of the tragic effects of bullying, or the misuse of drugs by ignorant and callous teenagers who have not been educated in basic kindness.  To blame these issues on drugs or "society with drugs" minimizes the severity of these issues and ignores how our attempts to eradicate drug use have made drugs more prevalent and more dangerous.  I just noticed this thread in the "recent comments" feed and this has probably been said already, but: dealers do not check I.D.  Tobacconists and liquor stores do.  Youth are bombarded with deceptive, hysterical anti-drug advertising that, because we are not stupid, makes us more likely to mistrust any drug education and less likely to use drugs safely. 

Drugs exist.  They're very, very difficult to control in the way that I think you are advocating.  We have been trying, brutally, for decades, and what we have gotten is similar to what eventually led to the ending of Prohibition.  If you keep tightening the thumbscrews, it will only get worse.  The dangers associated with drug use cannot be effectively addressed by the criminal justice system.

Anonymous's picture

The thing with drugs is that

The thing with drugs is that they result in other peoples injuries, as well as their own. They cause people to have some sort of dependency on the drug, so that they feel as if they can't be happy without it. This can ruin lives. Some of you might argue that it is your life to mess with, but the fact of the matter is, it doesn't just mess with your life. It messes with your parents lives, it messes with your kids lives, and it messes with your friends lives. Taking a tablet of shrooms is much worse than drinking a few beers. A friend of mine while tripping on shrooms, ran down the streets naked. That is not safe. While I do agree marijuana has a strong case to be legalized, I don't see any other drugs that such a strong case can be made for.

Serendip Visitor's picture

Tablet of shrooms?

Obviously, you have no idea what you're talking about at all. Shrooms aren't taken in tablets, they're mushrooms. Guess that was a little hard to find out for you? Think before you talk. And also shrooms and acid aren't the same drug. I trip every now and then, and have never ran down the street naked. You're friend is just an idiot, and if he can't handle the drug then he shouldn't take it. Plus acid has less potential then any other drug i know of to be addicted to. But it's fine to pop you're presciption anytime you feel like bc it's legal. I know too many people who are hooked on perks, oxy etc. Or can't go to sleep without popppin some xanax. Pull the wool from over your eyes and see how it really is, and don't come on here and feed all these people this garbage info

Serendip Visitor's picture

you're making a sweeping

you're making a sweeping generalization of the effects of drug use. Your experiences with LSD, ecstasy, shrooms, weed, etc are completely different, as are the long-term effects of the drug. Not all drugs result in dependency, not all drugs result in injuries. Your one friend tripping on shrooms ran down the streets naked, but does that mean all people tripping on shrooms will? Of course not.

Anonymous's picture


I've been using Cyclobenzaprine to relieve back pain. However, the drug also induces hallucinations, which is why I have to stop using it.
Just last night, I heard my sister come into my room and repeat the word "Jealous" several times before creepily walking away and closing the door behind her. I was completely freaked out. I thought of going out to ask her if she was truly in my room, but that thought and her presence in my room all occured while I was still asleep. It was so vivid. And I don't really remember my dreams but last night I was more awake than I've ever been in my dreams. I remember it all so well, that it all seems like I was awake when it all happened. I am so freaked out now. I feel like I woke up twice, once when my sister walked in and out of my room and again this morning.
If this is what hallucogenic drugs do, I don't want any of it. It's like being awake in a nightmare.

Dandy's picture

Cyclobenzaprine and

Cyclobenzaprine and recreational hallucinogens are extremely different from each other. However, I have taken high doses of benadryl and gotten effects which are very similar to what you describe.

Anonymous's picture

Bad Trip

this is called a bad trip. I wouldn't let it change your perspective on the subject

Anonymous's picture

Ive tripped off of dmt once

Ive tripped off of dmt once though I do not think I did enough, but I did trip pretty hard it was a crazy experience everything just slowed down tremendously and my perspective of everything I thought and saw completely reversed. Ive also done shrooms alot of times and once I had a really bad trip where some shadowy figure was following me and everything just seemed evil but at the same time Ive had some of the best experiences and revelations from eating mushrooms and i dont regret any of it. Since my bad trip though Ive had trouble looking people in the eyes and holding conversations thought its getting better now. But being as ive also tripped off of 2ci twice and acid once, i feel just much more lost in my thoughts than i used to and I am much more into how i view the world and my actions and becoming a better person rather than material things. Its really made me a stronger and more open-minded person. Ive also hasd some intense religous understanding and experiences while tripping

Anonymous's picture

long term affects

does anyone know if taking an excessive amount of lsd can cause severe back problems after not using for more then a decade? and if so are there any specific treatments for the back to be functional again? plz e mail me

fred's picture

I am a drug and alcohol

I am a drug and alcohol therapist. I have a 15 year old male client who disclosed that he used a significant amount of LSD durint the summer of 2009. He reported that he administered the drug though his eyes. He states that he has not used LSD since that summer. He is currently experiencing paranoia, anxiety, and periods of depression. How would you suggest he be treated for his current symptoms?

Anonymous's picture

I am 22 years old and when I

I am 22 years old and when I was 19, I tried acid. I've taken a total of 3 little square sheets separetely (at different times). I have been completely drug free for almost a year. I used a little pot and no other drugs for over a year now. Pot is the gateway drug and if other drugs get tried, i don't care who it is, the person wants to go back to the way they were, who they remember, and how they were happy. Today, I smoke cigarrettes and I believe they may be hindering me from greater progress. With the stresses of life, and moving on from my mistakes, it's a little draining, i try to keep going though. Sleep is not the way it was before. Sometimes I can tell that I am still just learning. My advice is to try to help with structure, responsibility, and morals. It's most appreciated when a drug user says I don't want to appreciate drugs anymore.

Peace of mind's picture

Church of ministry of deliverance

He needs to go to a ministry of deliverance church. While under the drug spirits enter him and are now reciding in him. Only God could free him by the power of Jesus Christ he will be set free.I went through the exact same thing. This is Real...He needs to talk to the deliverer from church. God Bless You and him.

Dillon's picture

I am a 20 year old who has

I am a 20 year old who has used LSD and many hallucinogenic drugs many times. It is my personal belief that hallucinogens start to erase the line between the conscious and the unconscious mind. When on these drugs I can feel all sorts of repressed material coming up, or just things I wasn't previously aware of about how my mind processes information and experiences. These drugs have been shown by science to slow our brainwaves into the delta and theta waves associated with the unconscious:

"Theta Brainwaves engage inner and intuitive subconscious. You’ll find theta in places where you hold memories, sensations and emotions. Sometimes, we also store secrets there, which we block out in times of pain, to survive what we feel unprepared to fix."

'Brainwaves that Talk Back' by Ellen Weber

If I'm slightly uncomfortable with a person or situation while sober, it can sometimes seem unbearable while in the hyper-sensitive state induced by the drug. Or I can see why something made me uneasy before, and can figure out how to integrate it into something I can enjoy. If people can't handle the material coming up, they spiral into a "bad trip" of hopelessness and terror. Imagine having a terrible nightmare but not being able to wake up and not having the relief of your conscious mind being absent.

However because of this some of the most transformative periods of my life have come from using these drugs. They help me see how I interact with the world and how I can hopefully make it better. When I say transformative, I don't mean instant enlightenment in a convenient single-serving size, I mean I watched myself fall apart and then build myself again in a better way only to fall apart again.

So, to help your kid, you should maybe let him know that he's not crazy to be depressed sometimes, anxious sometimes, or anything else. It's just some of the music our minds make while trying to figure out this strange life we get to live. Tell him to not to resist the way his mind is working, because it only makes it worse. Letting go is the best way to free yourself from emotional pain. Ask him what, specifically, is making him feel the way he is. Then maybe evaluate why these are false views that only bring him pain. I believe that depression and anxiety are our bodies way of telling us that the way our mind is working is hurting itself.

I'm not really a psychologist, but hopefully me giving you a little better understanding of what is going on in his head will help a little.

zander's picture

help or advice?

Primary school age 11 i took my first bong with a friend and it never really appealed to me at first i left it for a while it was not until i reached secondary school age 13 that i got roped into cannabis more often. Then ended up a daily thing for me years this went on i am now 20 years of age and just went cold turkey 3 weeks ago. also threw the years there was a lot of party pills Ecstasy and Metradone. 3 weekends ago i took a few 2CB hallunagenic pills three times in a week. The first time was a great laugh and enjoyable experience. After that me and a friend had one during the week had a good laugh! The third time I took another full one. I experienced a really bad trip and really wanted the feeling to end. My friends tried to calm me down, but it didn't work. I was so terrified! The hellish trip lasted a few hours, but gradually faded away. I felt really paranoid and couldn't trust the people in my company. My head was hurting a lot and I was really tired, but couldn't sleep. Ever since that bad trip, I feel really confused, this had lead me to think that the side effects of the eventful night may be permanent. I have gone totally cold turkey from all drugs since that night. I feel a little bit better, but I still feel like my mind is confused and that I have lost touch with reality. I have also experienced flash backs of the night. This has lead me to suffer panic attacks, migraines, confusion and anxiety. My real concern is that I still do not know if these symptoms I am experiencing are linked to cannabis withdrawal or the bad 2CB trip. If anyone can relate to this or has any relevant knowledge on this subject I would really appreciate feedback. Thank you. how long do you think this can last?

Anonymous's picture

probly not the weed, in fact,

probly not the weed, in fact, that could possibly help. ive had a few bad trips, and my advice is to try to have fun again. brain damage is very unlikely. however, if u still feel off dont hesitate to talk to a doctor. that may sound like a scary proposition, but there is no way he could get u in trouble especially if ur clean. dont worry so much, that isnt helping

Fletch's picture

Your experience with LSD

Hello there!

I was reading your reply about LSD and thought damn, what a smart guy. I've done LSD quite a bit and seem to perceive the drug the same way as you, and was wondering if you would be interested in further discussing it with me? Please email me( if you decide to reply, I would really appreciate it.

Prozac Dosage's picture

Hallucinogenic --> physical

Hallucinogenic --> physical and psychological effect on humans - alteration in the brain.
May cause panic, confusion, suspicion, anxiety, and loss of control.
- Personal change
- Complex action potentials and activity.

It might be the best if you have no any disease so that you don't have to take any drug and have no side effect. But if you have some disease... you have to take the drug completely according to the recommendation of doctors.

Anonymous's picture


we all have choices in this life, whether or not to take drugs is "your personal freedom of choice". I enjoy taking the odd drug, I' take mdna, ecstacy, acid and weed every now and then. I'm not much of a drinker (takes foul to me), but i REALLY enjoy my occassional trips when in the right environment. Guess what i want to say is that = you have this freedom of choice, but remember, there are always going to be consequences for your choices in life. You can never take from without having to give back... so enjoy your trips (as i do) but remember, you will not be free from the consequences, as with anything in life... love and light x

Anonymous's picture

umm ur doin illegal stuff so

umm ur doin illegal stuff
so the real answer is DONT DO IT
dont listen to idiots like him/her
its not good at all :)

Anonymous's picture

DMT is a very powerful

DMT is a very powerful hallucinogenic and is created by the body. How can this be illegal if your body produces this substance? Cannabis has shown positive aspects if you look into the research, aspects which the governments and the media have downplayed or overlooked in their hype and hysteria.

Yes drugs are very powerful, but so is the mind. If you have the right mindset for it then it can unlock so much potential. Life is simply a journey, and drugs can often lead to experiences that you would otherwise not have. If you do anything to excess it is bad for you. And who is to say that legal drugs such as caffeine, alcohol and nicotine are not as harmful?

If the idea of drugs scares you, don't do them. If you feel paranoid about the thought of them, don't do them. If you feel your mindset is not secure and open, don't do them.

I'm not going to go around publicly advocating drugs, as it is not for everyone and if you feel ready to do certain drugs than it will come naturally, not through peer pressure or misinformation. But what people choose to do to their own bodies is their business, our physical and spiritual journey's are our own. Making drugs illegal drives them underground and possibly leads to more people taking them negatively. Look at Amsterdam, it had legalised marijuana and magic mushrooms, and the hard drug use is lower than many other cities, people aren't all crazy there and there is not a large number of crime etc.

All you can do is inform and guide, it's not for you to say what others can and cannot do, you can only lead your life by example, following your own path. Love and light x

Anonymous's picture

What IS illegal?

Who's to say what is or is not illegal? sure when people trip, they sometimes do stupid things. But saying that you shouldn't try something just because it's illegal is extremely close-minded. calling someone an idiot for expressing an opinion that is different than your own is childish. people do have a right to make choices. so maybe doing drugs is illegal. so is drinking under age. so is smoking cigarettes when you are under 18. people do that and they aren't looked down on nearly as much as people who smoke pot, or do pills or other such drugs. i don't think that's fair. drinking and smoking are normal things in society and that's why it doesn't seem so bad. people are uncomfortable with things that they aren't used to and when you're uncomfortable with something you become very opinionated and against it. you should be able to live your OWN LIFE without being subjected to that kind of judgement. you should never do anything you don't want to, but you should also never let someone stop you from doing something you want to do just because they say you can't. live your life.

Anonymous's picture

help with recovery

Does anyone know any websites or books that help with recovering from shroom usage? I only tried it a few times but I'm sure it's triggered something because I've felt awful these past few years and don't even feel like the same person anymore. (Btw I also smoked weed on a regular basis for 4 years and tried ecstasy, cocaine and amphetamine a couple of times each.
My whole thought process has changed and I'm always in my head. It takes me 1-2 hours to sleep (unless I'm exhausted) because I keep having these incoherent thoughts. I also hear voices, not like they're in the room, but like they're in my head. They don't speak to me or anything, it's more like I'm replaying words and half sentences that I've heard before. It's weird.

My memory has also gone to shit. I once watched a whole episode of the simpsons while I was high and the next day I watched it again not realizing I had seen it the day before. I know this might not be that unusual but I'm still struggling with my memory and I'm clean of all drugs. Like if I read something and I try to retell it seconds after I can't. Nothing sticks.

I've also been dealing with depressions probably because my dad and brother died from cancer, which my mom had too. I'm sure it's all connected.

Dandy's picture

Weed and shrooms are both

Weed and shrooms are both likely to increase symptoms of schizophrenia, even if you didn't have them before.
Weed can give you memory problems, as can short-term use of ecstasy.
Try to be as healthy as possible, eat good food, exercise, try to sleep normally, interact socially, and your recovery will speed up. Not that you are recovering much, but being healthy in every way you can will certainly increase the chance and speed of recovery. How long have you been completely clean for?

Anonymous's picture

there is no recovery.

its not the drugs. what your experiencing is called schizophrenia. its a hell of a drug in itself. I know. you feel discontent in life because your constantly seeking answers for unwordly ideas. You should listen to those "incoherent" thoughts sometime, you might learn something about yourself, the world around you, and the way those two relate. The physical symptoms you display are not harvested from drug usage especially if youve only tripped a few times. The voices you hear are just your mind catching itself from falling into a delusion. just a side effect of your brains special brand of chemical reactions. as long as you keep them in check by knowing theyre not real and not letting them play on your emotions your fine. schizophrenia is more then that though as a whole. its a neccessary evil that, whether you know it or not, you choose to have. But once your schizo, you dont go back, you cant unrealize things. Just keep your delusions in check, moderate your drug use(with the exception of hallucinogens), and dont seek the internet next time your bored, take some shrooms and learn about yourself.

P.S. if you feel depressed all the time stay away from seratonin reacting drugs like most uppers. coke is real bad. MDMA(ecstacy) is also a really bad idea. Your nerve cells are runnin on empty after a burst of your happy chemical so you'll get bummed for up to a few months after

darjmorton's picture

spiritual health and the use of DHA omega 3

Hey not only could you consider the spiritual side of things by considering putting your faith in Jesus Christ, who can deliver you from all this confusion...he died for your sins and rose from the dead so you could have eternal life....

also large doses of DHA (omega-3 fish oils)could help you, they improve nerve plasticity (brain functioning health) and can certain help your brain heal and help you think and feel better, i have tried them, you do have to ensure you are taking high doses but it does help!

DHA is essential for the proper functioning of our brains as adults, and for the development of our nervous system and visual abilities during the first 6 months of life.

DHA deficiency is associated with cognitive decline. PS controls apoptosis, and low DHA levels lower neural cell PS and increase neural cell death. DHA is depleted in the cerebral cortex of severely depressed patients

Fish oil supplements: 3,000 - 4,000 mg standardized fish oils per day. Read the label to check levels of DHA and EPA, which are not the same as mg of fish oil.

in the field of omega-3 research recommended minimal daily intakes of 220 mg DHA/day for adults for overall human health (including brain functioning) and a total DHA/EPA intake of 650 mg daily. check out

Anonymous's picture

To: help with recovery I have

To: help with recovery
I have been through the exact same thing as you. Just minimized in the amout and duration of abuse. I was addicted to ecstasy(No matter what people tell you YOU CAN GET ADDICTED TO IT) for my entire freshman year of highschool. I would also smoke marijuana and do cocaine every now again. But ecstasy was my main drug. I would take 2-4 pills once every week for awhile. The last time i did it, on the 4th of july, I noticed right before i was about to peak that it felt too good to be true. And it was. So I stopped for good. But after my memory loss was terrible. If I read anything I'd literally forget everything right after i started a new line of a paragraph. I was also depressed until around last christmas. As for the voices in your head, that's most likely from amphetamines. Amphetamines while your on it can produce auditory hallucinations. So if you did it frequently it would make sense that it can spill into your sober life. I am happy to inform you that those side affects your talking about are temporary. I am free from depression and my memory is excellent now. But since your experience of drug abuse lasted longer than mine, I'd have to guess that your recovery will last longer as well. Last time i rolled was july 4th, 2008. I noticed reduced feelings of depression around the month of December 2009 and today i feel completely fine. I hope my comment helped you and please just believe that you can feel better without drugs, and you will.

Peace of mind's picture

Altered mind

I went through the same situation, but believe it or not it was with smoking so much marihuana. I guess im hypersensitive. anyways I develop all sort of mental disorders except skidzofrnia. It was a total nightmare. I was healed by the grace of God. since i could never sleep for 5 months because of so much uncontrolbl thoughts, i even felt my mind wasnt my own. So I prayed, prayed, prayed. It got worst before it got better. If you do not believe in God and the existance of the devil. Do believe, they are real, very real. And when we take any type of drug that alters our brain. The spirits get in through your space in time while in the drug. If you want to be free go to a church that ministers deliverance. And I assure you in the name of Jesus, that U will be delivered of all of them. May God give you understanding. For we are not against flesh and blood but against rulers of darkness.. Ephesians 6:12. God freed me He could free U too, if you trust in Him. God bless U

Anonymous's picture

ive had similar issues with DMT

I feel your pain here friend. I had similar experience with DMT back in Oct. 09. Had a very bad mental reaction to it, psychiatrist said these things get better over time.

don't worry though, i used to take shrooms and i found DMT to be the chief in mind blowing mind raping drugs. i sit around at times and wonder if i died during that experience and i am stuck in some alternate reality that is really a synthetic joke being played on me. but the few weeks after taking it i had some similar symptoms as the ones you describe and i have noticed some improvement.

there is no real information on the internet for recovering as hallucinogens are such a mystery anyway. you just got to move on and find a foundation to start from. maybe even start over with your idea of who you are.

Anonymous's picture

I agree with you completely.

I agree with you completely. Though i have never experienced DMT, i have had a negative experience from a bad trip on shrooms. It was like i watched myself fall apart and was forced to face everything i have ever feared and repressed memories and feelings associated with those memories. It took me awhile after the trip to recover, but all you need is time. I couldn't handle thinking about the trip for awhile. Eventually, I really started to contemplate the reasons for experiencing the bad trip and after i really felt like i knew the reasons, i let go of them. And from there, i have been able to build myself up by changing for the good. And i fully push your idea of starting over with your idea of who you are. I realize now that i was never really sure of who i was though i thought that i knew for sure. It was hard for me to accept some of the aspects of who i was and now i know that the only way to live is to accept who you are and embrace it. I cannot say that i am done with this journey. I am nowhere close because it continues the rest of your life and only you have the power to control it.

Jackhammer's picture

Just be happy and love

If you want to do drugs then do them, if you don't then don't. But, don't try telling someone else what to do because it is a personal decision. We have the right to live our lives the way we want to. I personally enjoy smoking weed, tripping (acid, shrooms), and rolling on E. They have all helped me learn more about the world, and have expanded my mind. I'm in college and get good grades and am not ruining my life. I do not regret the drugs that I have taken. I smoke weed on a daily basis and see nothing wrong with it, with acid ,shrooms, and E, I do every now and then, but I don't try to go overboard with them, because they are not the best things for you I will admit, but I love doing them.

Anonymous's picture

Shrooms and LSD have given me

Shrooms and LSD have given me a deeper understanding of life and spirituality. Everything just suddenly makes sence when you are tripping and it is the greatest feeling in the world. The entire planet seems to be able to breathe and takes on a new life. The trick is to write down everything that you are able to realize while having this epiphany and integrate this new found happiness into your everyday life. In contrast, shrooms were mostly visual while lsd seemed to effect the mind much more. Tripping is not for everyone. One most be open minded and in the proper mind state to truly appreciate what is happening during their trip. Also, they must realize that they are tripping and that this experience is only temperary. Don't be scared, embrace every second of it and love it! Be in the presence of friends and in a comfortable environment. Watch a chairlift video and take a look outside. --- LSD --- Best experience of my life.

Anonymous's picture

Oh when will people realize

Oh when will people realize how bias their opinion truly is? If you have not experienced or experimented with any drugs your opinion is based solely off the accepted opinion of the media and bias statements/thoughts. The only legitimate argument of any of the ranting, anti-drug individuals is that it kills brain cells. Any other situation/occurrence such as death and addiction are based on individualistic physical condition and mental state, therefore can not be a platform for further argument. If you don't agree, I would truly like to hear why.

Anonymous's picture


I agree, all these people going on about drugs who have probbly never tried it, they dont know what their talking about, its like me going doing some surgery off some one, with out any qualifications and just performing it of how iv hurd how to do it through other ppl who dont know them selfs. their what you call closed minded individual who have led such sheltered lifes and let their minds be rulled by the state and the media, so that we all behave and act in a way that other people find "apropriate". no one has ever died directly from ketamine, acid or any other hullucigan drug, just people taking them in silly places when their with the wrong kinda people and not in the right mindset. people how ever have died from ecstacy, but this is because they dont know what their doing, they dont drink enough water and dehidrate or they drink too much and dont do anything with their new found energy so they drown in thier own fluids. how ever their is that small chance someone can be alergic and die, but that can happen with anything.

Anonymous's picture

Risks are nessicary for life

Risks are nessicary for life to be worth living, but not all are worth taking. Drugs are one of those risks not worth taking, they are illegal, the kill brain cells, they will easily get you to do something idiotic and above all they can kill you. Now you tell me, is a couple hours of being high worth the risk of death, loss of inteligence, jail time (even small amounts of marijuana in your keeping is a $1000 fine and ay= year in jail)and destruction of your life in other ways?

Anonymous's picture

alcohol and sneezing also

alcohol and sneezing also kill brain cells. the argument of something being illegal is rediculous. It's government imposed. underage drinking is illegal. its terrible for you, but when you turn 21 it is suddenly okay? marijuana is used medically. its illegal to healthy people but not to cancer patients? drinking and driving kills more people than any other drug related accidents. You also can't overdose on marijuana like you can on alcohol. you just got owned by a 17 year old. have a nice day.

Anonymous's picture

Feh, amateur: In the future spare us your blithering prattle

Point 1: while it is true that sneezing kills brain cells, we have to take into account the question of magnitude. I believe that is is fairly common knowledge that most drugs kill more brain cells than does sneezing.
Point 2: The government imposes restrictions on drugs not because they want to deprive the individual of his/her pleasure, but because they are trying to protect the individual from some of the harmful effects of the drug, as well as preserving the functionality of society. There are other things that the government tells us is illegal, such as killing people. While it may float your boat to do whatever you feel like, there are repercussions both directly and indirectly that you must take into account.
Point 3: Underage drinking is dangerous because it interferes with specific parts of the brain that deal with development. The government set the drinking age at 21 with the hope that an individual at 21 would have a better (or more developed) sense of judgment, and in that, avoid indirect harm to his/herself. While it is true that the drinking age in other countries is significantly lower, this is due primarily to cultural factors.
Point 4: The reason medical marijuana is used by cancer patients is because the marginal benefit of using marijuana is much greater than the marginal cost. Cancer patients have more pressing issues to worry about than the physical consequences of marijuana use (like maybe cancer) To healthy people, the marginal costs are higher, and the marginal benefits are lower. Marijuana contributes to loss of specific neural functions as well as impaired immune abilities, heart problems, and reproductive problems.
Point 5: I fail to see your point that drinking and driving kills more than drug accidents. Does this somehow REDUCE the risk of drug use? No it doesn't. You are an idiot.
Point 6: Just because it is virtually impossible to OD on marijuana does not mean that it is a good idea. Again, you are an idiot.

BTW: I am also a 17 year old. You just got owned. Have a nice day.

Anonymous's picture


You actually believe you can trust your government to make anything unhealthy illegal? If that were the case Mcdonalds would be illegal. Cigarettes would be illegal. You make all these claims about how illegal drug use is "idiotic." Yet two of our legal drugs, tobacco and alcohol will account for more lost lives this year than any terrorist attack has ever taken. If the government was after your safety, why do they allow these drugs in our society. If the government was concerned with your safety, you wouldn't be able to walk into the doctor and walk out with a prescription for whatever drugs you want. Sure Doctors have "limits" and are "trained" yet prescription (LEGAL MAN MADE DRUGS) have a longer list of side effects than most illegal drugs. Coming from an illegal drug user, I WILL NOT touch prescription drugs unless my life depends on it. I do not drink alcohol. Don't worry I'm not naive enough to believe that illegal drugs don't have some kind of effect on your body. News stories everywhere keep telling you if you eat that much food you'll get fat. Guess who will live longer, someone who smokes weed on a daily basis, or someone who eats Mcdonalds on a daily basis? Thats right folks the stoner outlives the Fatty. And this drug is illegal because its hazardous to your health...

I'm not going out of my way to tell you to stop eating fast food, nor have I tried to get Congress to pass anything about it. Yet obesity takes more lives than marijuana and more money is spent to prevent marijuana use than obesity from food abuse. Sigh silly Americans maybe someday we will get intelligent, and actually have policies that will make sense when compared to each other.

Anonymous's picture

I used to be 17, and at that

I used to be 17, and at that point in my life I was just as ignorant as you.

Anonymous's picture

Well did you know that even

Well did you know that even running kills braincells and jumping so

Anonymous's picture

Ok to the first comment, What

Ok to the first comment, What doesen't kill brain cells? honestly.

Anonymous's picture

Yeah well that is coming from

Yeah well that is coming from a person who can't even spell in the first place and is probably swayed by the media and majority of society on about every topic in life. Make your own decisions, don't worry about other peoples. Your perception is quite bias, as it seems you have never experimented with drugs. Maybe I am just making unnecessary assumptions, but how can you say it is not worth the risk if you haven't tried yourself? And just because one experiments with drugs does not ensure addiction, it is called will-power and self control. It is people like you that create the drug hysteria in the first place.

Anonymous's picture


everybody is talking how they r either against drugs completely or for drugs completely. my personal opinion is that if u wanna b a druggie go ahead. i find it incredibly stupid how all the non-users try to get the users to stop. its their life. i dont do any drugs but i have had alot of friends and family members on some type of drugs. but also on the other side, i dont think users should pressure non-users into doing drugs. my druggie friends r the most fun to hang out with and they do say how its hella fun and all but they never pressure me into doing any type of drugs. drugs do kill people alot but so do many other things. ur not just gonna stop living ur life and taking risks just cuz it mite kill u, would u? but i do want to add that, while i dont care about drinking, i will kill anybody that drinks then drives. drunk driving kills other people. if it killed just the drunk person, ok, but usually the drunk driver lives and kills somebody else. i have had friends and family members even that have gotten into a car crash with a drunk driver. they died and the drunk driver lived. most times the drunk driver just drove away but i kno once he was caught and spent 20 years in my opinion it shoulda been more

Anonymous's picture

That's a fine choice, the pro

That's a fine choice, the pro choice approach. But can you give me any advice on how I can make sure my kids dosen't run into any of your friends? Drugies are parenting dope-head children. Then these kids distrubite drugs in school and ruin a lot of good students, and people. Parents should not have to raise their kids in a cave to protect them from your friends. And I'm not being judgmental either. Free choice is fine, but keep the junk in your closet. Don't spill it over into my life. With all the effort to protect my kids from such destructive things, you ought to expect to hear things said; things that you consider judgement.

Anonymous's picture

You can't keep drug dealers

You can't keep drug dealers away from your kids. It's just a part of growing up, and they'll have to make their own choices regarding drug usage. I'd rather have my kids exposed to the real world and not raised in a "cave".

I believe most things are okay in moderation. I went through a period in college where I was smoking (pot) and using other drugs (psychedelics, E, Molly, etc.)too often and I ended up graduating a semester behind because I had to re-take classes. Eh, if that's the worst that came of my drug use, I'd totally do it over again- maybe just in smaller quantities. Sure, you have to keep things in perspective and not let yourself get sucked into drugs to the point where you neglect your responsibilities... but I think controlled, responsible use of drugs, particularly psychedelics, can be a very eye-opening experience.

I never regret having dabbled in drugs, and to be honest, I hope that my son has that experience someday. I would never push drugs onto anyone, much less my own child, but when he comes to me and asks about them, we will have an honest conversation... I refuse to just spout off anti-drug propaganda, I would rather him be properly educated and make his own decisions.

Anonymous's picture

here's the thing about people

here's the thing about people ruining their lives to drugs:
the people that do that obviously were weak and extremely vulnerable to begin with, which is why they let drugs control their lives. but, most people aren't like that and can control themselves. people that are that weak shouldn't do drugs

Serendip Visitor's picture

Everybody thinks they are

Everybody thinks they are strong until they realize life can be a fucked up thing. You go through some shit that makes you think or freaks you out and it breaks you down. (For some people this can be caused by LSD or other hallucinogens, some by traumatic experiences, bad childhoods, ect.) After this you can rebuild yourself and then you are truly strong. It is all part of growing up, unless of course you are sheltered your entire life and never have to face some of life's toughest times.

Whenever you feel down just try and think: It is through life's hardships that we are able to learn the most and always try to think positive. ie What doesn't kill you (or seriously handicap you :P ) makes you stronger.

Anonymous's picture

open your mind

All those dicounting lsd and other hallucinogenics shouldnt be able to speak. ive tripped on many different things, such as 2-cb, mde, lsd, dxm(sadly yes ive done it) and others on top. each one lets u experiance life in a new way and develop your thinking in a new way. it lets u see the sides of life and able to comprehend things others cannot even imagine. it expands your mind and soul. your physical body WILL perish, but your mind and soul are forever, so why not augment them for the better and with things that is so little understood? what im saying is it will develop you into a more understanding person in all aspects of life. i say, for those with a hunger for knowledge, spirituality, or philosophy, try it.

Serendip VisitorEric M. Wiggin's picture


BROAD IS THE WAY THAT LEADS TO DESTRUCTION!!!!!!!!!!! Whatever youy have felt is spiritual, it must be on the fringe of the supernatural, and there is grossly negative (sinning or fleshly lust and the death which persues such) or there is the insanely positive (like the salvation of your everlasting soul), in the since of spiritual. Also I would like to add a Bible verse. Rev. 21:8 (of the Holy Bible) does not speak of a sorcerer (or one which uses witchcraft) who uses a mantra, or an encantation, but one that alters their mind with drugs--drug abuse.

Anonymous's picture


half of you replying on this are complete tools. for the people who hate on drugs, fuck off, if anything you know less about drugs because you stay away from them, where as we "users" and "law breakers" probably know what were talking about and isnt it our choice what we do with our lives?. for the people who want to try different things, my advice for you is, be comfortable about doing it (dont second guess), do it right (get high....dont cheat yourself), be with others who are on the same drug you are, and try to learn something from it. drugs are a very mysterious thing, and a debate could wage forever on whether or not they should be allowed, ultimately i think the best decision is for everyone to stick to their own. let me smoke weed everyday and any kind of drug that i want, its not your life, and im not affecting yours in anyway.

Summer Glau's picture

LSD? Don't mind if I do.

I have lost friends (mentally) to hard drugs, but I have also lost friends mentally to things that are not controllable like sexual abuse as a child, physical abuse growing up, and depression. I have experienced all of those and in my opinion weed and lsd saved my life.

I am probably still considered mentally insane, but I am now functional and easy going, whereas before drugs I was jumpy, angry, making bad grades, and just a total wreck.

Although my last trip was a bad one(I was geeking out and basically couldn't see things infront of me, I was just saying please help me over and over again every time my friend left the room), it was fun for the first few hours and after a few days I was back to normal, and am tripping again this weekend. It opened my eyes, man, completely and totally awakened me to so many wonderful things.

Basically what I want to say is if you don't want to do drugs that's fine, no one's going to force you. But do not let yourself be brainwashed by the goverment, know the facts before you form a definite opinion. My plan is to stick to weed and acid and maybe some shrooms or dmt, nothing addictive/life ruining like cocaine or heroin. In my opinion everyone should do acid at least twice in their lifetime, I bet on everything I love there would be alot less narrow-minded bigots and alot more love in the world.