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The Effects of Hallucinogenic Drugs on The Brain

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Biology 202
1998 First Web Reports
On Serendip

The Effects of Hallucinogenic Drugs on The Brain

Alicia Ebbitt

Hallucinnogenic Drugs alter a person's perceptions of reality and may cause hallucinations and other alterations of the senses. Drugs classified as hallucinogens include: LSD (lysergic acid diethylamide), 2,5-dimethoxy-4-methylamphetime(DOM), N,N-dimethyltrptamine(DMT), psilocin, and mescaline. There are two aspects of these drugs that classify then as hallucinogens. They all have common side effects, including distortion of sensory perception, and other psychic and somatic effects. These drugs also exhibit cross-tolerance. This means that a user of hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used and the shorter the time span is between the last usage.

Hallucinogenic drugs have been used throughout history for a number of reasons. They have been used as medicinal agents as well as having served religious purposes. Hallucinogens such as mescaline have been used in Native American ritual ceremonies. There was extensive usage of hallucinogens in the 60's and 70's as part of the counter- culture hippie movement. During the "acid tests" of this era, hallucinogenic drugs were used for mind exploration (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinogenic drugs cause both physical and psychological effects on humans. The physical effects of these drugs include: dilated pupils, elevated body temperature, increased heart rate and blood pressure, appetite loss, sleeplessness, tremors, headaches, nausea, sweating, heart palpitations, blurring of vision, memory loss, trembling, and itching. A user of hallucinogenic drugs will also experience a number of psychological alterations in the brain. These drugs may cause hallucinations and illusions as well, as the amplification of sense, and the alterations of thinking and self-awareness. It is quite possible to have a bad reaction to hallucinogenic drugs. This is referred to as a "bad trip" and may cause panic, confusion, suspicion, anxiety, and loss of control. The long-term effects of these drugs can be quite dangerous. These long-term effects may include: flashbacks, mood swings, impaired thinking, unexpected outbursts of violence and eventually possibly depression that may lead to death or suicide.

Quite a lot of interest concerning hallucinogens has been generated by neurobiologists and other scientists. The effects that hallucinogenic drugs have on the brain are quite complicated and very interesting. Many users of hallucinogenic drugs have experienced whole personality changes which raises questions about the relationship between brain and behavior. Scientists are also curious as to how total alterations of the senses can occur as the result of hallucinogen usage. Many people that have used hallucinogens claim to have "seen sounds" or "heard colors". Scientists ask questions such as: How can a person under the influence of hallucinogenic drugs see things that aren't there? or How do flashbacks work? Another aspect of hallucinogenic drugs that interests scientists is that they are psychomimetic meaning that they mimic certain aspects of psychosis. Through the use of hallucinogenic drugs, one can induce temporary symptoms of psychosis.

As a result of the great interest in hallucinogens, many years of research have been done to try and determine exactly how the brain is affected by these drugs. Scientists have tried to determine if there is a specific site in the brain where hallucinogens act. This has been difficult to determine. Scientists still are unable to answer all questions about hallucinogenic drugs. However they have been able to determine certain areas of the brain that these drugs do act upon.

Early on in the reasearch on hallucinogens, it was determined that hallucinogenic drugs structurally resemble serotonin (5-HT) Serotonin is found in specific neurons in the brain that mediate chemical neurotransmission in the brain. Neurons containing serotonin can be found in the brain stem section of the brain. Axons of serotonergic neurons project to almost every part of the brain, affecting and communicating with all sections of the brain. Serotonin also acts at many receptor areas of neurons. Because hallucinogenic drugs are structurally similar to serotonin, it was theorized that hallucinogenic drugs may act upon serotonergic neurons (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Scientists began to carefully study the serotonin system and found out that hallucinogens do in fact have some kind of effect on serotonin. Hallucinogenic drugs cause an increase in the level of brain serotonin, but they inhibit the rapid firing of neurons containing serotonin. This is a negative feedback system in which as the serotonin level rises, the activity of serotonergic neurons decreases. It was originally theorized that this effect of hallucinogenic drugs directly caused sense alteration and hallucinations. Several observations however have shown this theory not to be true. These observations include the following: Low doses of LSD effect behavior, but do not depress firing of serotonergic neurons, The behavioral effects of LSD outlast the alteration of the firing of the serotonergic neurons, Repeated dosage of LSD results in a decrease of behavioral changes, but still effects neuron firing, Other hallucinogens do not affect serotonergic neurons, When serotonin levels are depleted, the effectiveness of LSD is not eliminated (Ian Leicht, "Postulated Mechanisms of LSD").

It has now been determined that the effects of hallucinogenic drugs are actually caused by the effects that hallucinogenic drugs have on the post-synaptic activity of serotonergic neurons. Hallucinogenic drugs directly affect the serotonin receptors(specifically the serotonin receptor subtype, 5-HT2), which is what eventually results in a complex pattern of action potentials and activity. This was proven by the fact that the depletion of serotonin levels in animals does not result in a decrease of behavioral effects caused by hallucinogenic drugs (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinations and other effects of hallucinogens are however very complicated experiences. They are not simply a part of a cause and effect system in the brain, where hallucinogenic drugs act on serotonin and cause hallucinations. Instead, hallucinogenic drugs act initially on the serotonin system, which sends into motion, a pattern of complex action potentials and activity. Other neurotransmitters may be involved in these activities as well. The effects that inputs and outputs have on each other in this system as well as the pattern of action potentials mediated by hallucinogenic drugs help to cause many of the complex changes that allow hallucinations to happen. (B.L. Jacobs, "How Hallucinogenic Drugs Work") Scientists continue to do research to determine the exact effects that hallucinogens have on the serotonin receptors and to answer any questions that they cannot yet answer.


WWW Sources

1) NIDA (National Institution Drug Abuse: LSD(Lysergic Acid Diethylamide).

2) Hallucinogenic Drugs in Psychiatric Research and Treatment: Perspectives and Prospects.

3) Tryptamine Hallucinogens and Consciousness.

4) Hallucinogens (PCP, LSD, etc.).

5) Narcotics, Dangerous Drugs, and Marijuana.

6) Healthguide Online: Substance Abuse: Hallucinogens.

7) Hallucinogens.

8) Los Angeles Police Department Drug Recognition Expert Unit: Hallucinogens.

9) Postulated Mechanisms of LSD.

10) B.L. Jacobs. 1987. How Hallucinogenic Drugs Work. "American Scientist". 75:385-92.

11) M.C. Bindal, S.P. Gupta, and P. Singh. 1983. QSAR Studies on Hallucinogens. "Chemical Reviews". 83:633-49.


Comments made prior to 2007

When you list the drugs in the beginning of your article you list lsd psilocin and mescaline. But "psilocin" is not actually the active ingredient in hallucinogenic mushrooms. The correct term is "Psilocybin". Just thought I'd point that out ... Daniel, 19 February 2007


Eric Wiggin's picture

My response ti Lsd25--Biblically correct.

You do know that all the perspectives & behaviors that go on in a group that calls themselves a Christian Church are not always that correct very proper, or even at all just, and it all is not doctrinally correct, according to our Holy Bible (?) . "Lsd25", you are not an abhorrence-- not even at all. It is a good thing that we have those people like Crick. These sins of substance abuse are abhorrent, not you-- and not Crick. We all need 2 know God far better. If we blow our minds w/ drugs or w/ too much alcohol; if we lie chronically, steal, or we are sexually immoral we continue to hinder our own quest, our effort to know God.

joe kimmel's picture

yeah lmao

drink the kool aid already bro lmao

Teacher Steve's picture

Uh huh

I lost count of how much acid I dropped. In 10 years of play, I had 1 bad trip, it lasted for 3 days. Sorry you bummed out man. Maybe your depressive state of mind about carrying a major physical disability rode you down.

joe kimmel's picture

thank you! i lost count in

thank you! i lost count in about 7 months of dropping hits but people post idiotic untrue hanus comments about lsd which is one of the least harmful chemicals known to man

A Dogg's picture


Just trip with a group of people or a good friend and your good to go. I've tripped at least 25-30 times on acid in my high school days mainly and never had a bad trip. I haven't seen acid in a long time, since 05 or so, but it is a magical journey I would encourage anybody to experience at least once. P. S.-why is a blind dude eating acid anyway doesn't that kind of defeat the purpose just a little bit. (not meant to be mean just honest!)

Bear frequency 's picture

blind on lsd

Actually as a someone who is colorblind, that wanders in the power of LSD I have to say that it opened my eyes to a whole new world the very first time I took it. I was no longer color blind for 15 hours and at first I was confused but once I've accepted it as reality I simply enjoyed it. One's ability to see does not take away from the trip LSD takes effect on all the senses and hallucinations will still happen to someone blind. It's not indefinite proof but I did have insane visual, audio, and tactile hallucination in complete silence and darkness.

Serendip Visitor's picture

"Depressive state of mind

"Depressive state of mind about carrying a major physical disability?" Come on, is that a joke? I know this isn't some forum, but that is ridiculous. Why is he depressed because he prefaces a story with situational information? LSD isn't for everyone. Truthfully, it isn't for anyone, just a drug with mixed (and unique) physical results.

Serendip Visitor's picture

i absolutely agree with the

i absolutely agree with the person who said drugs arent for all of you. the phrase "use it dont abuse it" is soso true. i love drugs, im not even addicted. i roll smoke and try diffferent hallucinogens every once in a while, have a bad ass time, and then go about my daily routine. simple as that. you guys are just weak and let the drug take control of YOU...

joe kimmel's picture

AMEN ! i just dont like x but

AMEN ! i just dont like x but you spoke my mind

Serendip Visitor's picture

It is not a matter of weakness

Addiction is characterized by a compulsive inability to control temptation of just about any behavior. An addict must replace the negative behavior with positive behavior, but its more about relocating your addiction to a "healthy lifestyle" than it is curing it, or suppressing symptoms. That's why an addict is, at best, in recovery, and never cured. Some people might argue, but I'm well educated in the twelve step programs, and those sorts of programs are, imho, a form of addiction replacement.
But it isn't about a weakness, or "letting the drug control you" and its actually really offensive.

Serendip Visitor's picture



joe kimmel's picture

you must just have a mental

you must just have a mental disorder ecstasy does more harmful things to your body than hallucinogens..people who are mentally unstable are the only ones affected negatively by lsd or any hallucinogens

Dr. Nelson Orr's picture


Anyone can have a bad trip. Perfectly healthy people can develop mental issues from taking psychoactive substances because of the way that drugs like LSD operate on multiple different systems can change your chemical makeup permanently.

For example, a close friend of mine trips acid regularly. She now sees Tracers permanently, even while sober.

People say LSD is not addictive, but it is.

Also; perfectly healthy people can trip acid regularly enough and develop an "Acid Character". This is similar to what happens when people abuse alcohol, and develop beligerant or excessively happy personalities only while under the influence of the substance.

I'm an advocate for free use of drugs. Just know what you take. Be prepared to split your consciousness in half.

asim's picture

y did u saw fish tank

its simple u hallucinated due to the effect of those pills..hallucinations are not always due to mental disorder smtyms due
to effect of drugs...under d effect of drugs lyk toluene u hallucinate
mostly wen u are not thinking about anything but simply in a blank
memory state..wateva u hallucinate are stored der in sm parts of
memory(mostly past things) the memory retrieves it occassionally and shows dem to u ...i m sure u wd hav seen sm fishes o aquarium o sm movies on fishes o smthing lyk dat...i hav even worse hallucinating experience dat almost killed me thrice..but i love to be in dat hallucinating world

Evan 's picture


Anyone here broken through the veil?

Serendip Visitor's picture

psychotropic hallucinogens

ie; Zyprexa = Hallucinogen, anger,anxiety,dis-inhibition,etc
is there any reason this link above isnt working,? (Hallucinogenic Drugs in Psychiatric Research and Treatment: Perspectives and Prospects.)i wonder why mental health would give people on a drug psychosis hallucinogens ? I bet no one can answer this properly and make sense.

rawr ness's picture


can any drugs help with obesity?

Teacher Steve's picture

can any drugs help with obesity?

Amphetamines. They will rot your internal organs if you take too much too often. Docs prescribe them as "fat pills" with low dosages therein

lasie2005's picture


Just a balanced diet, plenty fruit and water and vegetables

rachel's picture


no if your fat your fat

asim's picture

to get rid of obesity

try honey wid water every morning...u ll get rid of obesity

Serendip Visitor's picture


no...drugs make u fatter...unless u do meth or heroin...but why wud you do tht?..just keep smoking weed and try not to eat so much

Serendip Visitor's picture

no not all drgs but ive

no not all drgs but ive noticed speed makes me un hungrey you shoud try it!!!!! meth for lyfe

kanye's picture


no more drugs for me.
pussy and religion is all i need.

Serendip Visitor1's picture


baby we'll live a hell of a liife...

GIFT's picture

stay away from trying to see

stay away from trying to see death
ive been there and back
read this and rememeber
just imagine everything youve ever had and shatters right infront of you. Then you become a lifeless robot seeing everything you wanna touch but you cant, its amazing after you come so close to death, you dont know what you got till its gone
that guy tells the truth with that song, i know this wont prolly get read by anyone
but this is the only drug i havent done. And its what causes you to lose your minddd

Serendip Visitor's picture

um....speak from experience?

i dont like people who speak as if they know what they are talking about and then admit that they dont. it causes you to lose your mind? yet you havent done it? sounds pretty bogus to me.

Serendip Visitor's picture

It is common knowledge

It is common knowledge that drugs cause you to loose your minbd especially ones like LSD so I say it is pefectly aceptable to say such a thing on a page dedicated to hallucinogenic substances and their effects. Loosing your mind doesn't confine you to a negative thing, sometimes it is enjoyable!!

declan's picture

'losing your mind' is such a

'losing your mind' is such a ridiculously vague term it holds no value in this context. And it is more a perspective change, than losing your mind.

Serendip Visitor's picture


Right on man you don't know till you try it describing tripping to someone who's never tripped is impossible

Drake's picture


This is so true even though I have only done boomers ( shrooms) I have felt the effects and loved it. Even though for me personally I have felt empty the next day didn't want to eater drink anything ( which me and my friends refer this as a hangover) but over all the feeling of them is exciting and a thrill ride. And for the people who think you see stuff it's a lie u see tracers maybe breathing walls if you do LSD but nothing crazy if your with a friend and your both doing it put in a movie and just go for the ride ( g rated movie anything more well your on your own) it's deffinly worth trying and for the people who say it ruins your life it doesn't if you don't do it often.I felt greater at my creative side of me and my thinking became stronger and more open to new things.

Buds123's picture

I don't know

I love smoking weed and homespice, but i want a stronger high. I want to try mushrooms, but i'm a small girl and i'm not sure how many to eat or anything. I'm 5'3 and 111 pounds. Anyone have any suggestions?

Drake's picture

Don't take acid before you do

Don't take acid before you do shrooms because it's easier to describe acid after you do shrooms idk how to really say how much to take I would do half a eighth first that will give you a buzz like weed but 3 times that of weed really not trippy effects everything you can still do just you'll be happy and feel good and if you want to do more I wouldn't do more that a eighth to yourself me and my friend done them together which you always want a supervisor or baby sitter we kinda did till they got bored truing to put us in a bad trip we did 4.5 grams each which if your crazy enough don't go over 4 grams because beyond that it gets iffy and you have no idea where your mind will go :) but rock on girl

Evan 's picture


i would suggest that you take anywere from 1 gram to around 1.5 or 1 tab of acid. acid is a much more mellow trip and mushrooms give u a higher chance to have a bad trip just make sure your in a good environment.

Serendip Visitor's picture

try half an eighth your first

try half an eighth your first time...anyone who says you have to eat a full eigth is stupid because you can have really strong trips on a full eighth that could be scary if youve never done them before, different types are stronger you never really know. and you have to weigh out a half eighth because you cant just say oh eat like 3 mushrooms or something

Serendip Visitor's picture


id say u should eat a half of one to see how it feels then if u feel nothing after 30 min eat the rest of it....

Serendip Visitor's picture

make sure they're legit

make sure they're legit (trustworthy dealer) and start with a low dose..I'm an experienced tripped, weighing 150 lbs and I only need 1.7 grams to get a full-blown intense trip. Start with a small cap, maybe .5 grams and wait an hour to see how you feel. If you can do more, keep upping the dose by .5 each time. Mushrooms can be extremely intense and disorienting, so be careful and enjoy!

Drake's picture

Haha I love this but why only

Haha I love this but why only so low of grams I tried 4.5 with a friend and to tell ya the truth it's the best feeling ever!

Kristen's picture

Yeah, but how much do you weigh?

You can't tell someone to take 4.5 grams of shrooms for their first time when they only weigh 111 lbs. Come on! Listen to everyone else and partake in only 1/2 an eighth for the first time. That should be perfect for someone of your size. How much do you weigh (the person who suggested 4.5 grams)?

Anyway, I have done both shrooms and acid. I never had a bad experience with acid, but shrooms on the other hand was a different story. I took slightly over an eighth of shrooms the last time I tripped which was seven years ago. I experienced a nine hour trip, five of which was Hell on Earth. I lost my mind. For three years afterwards I had so much trouble sleeping. I would literally make out demon faces in any thing I focused on in my room at night. Now, I am a true believer of not experimenting with any type of hallucinogens, because you never know when you will receive a strong batch that could completely change your life for the worst. I also believe that any type of mind altering drug could make someone mentally unstable, and they could experience feelings of psychosis and depression if a bad trip is experienced.

Xavier's picture


If you used mushrooms only one time that can gace to you a negative result in your brain?

Saul's picture

My experince

I'm 18 and I started smoking pot at 16. I loved it. I'll always remember it. After that I started doing some research on other drugs. About a month ago I got some shrooms. Me and a friend tripped together. We also had some other friends with us, but we were the only ones that ate the shrooms, the rest just smoked weed. I loved it! =D There were points when I started freakin' out, but then I thought about how I knew that it was just the shrooms and everything was gonna be alright. After that I was fine.Then about two weeks ago I started doing molly. I went overboard. I almost cleared my back account on it. I didn't have any self control. It was terrible. Then one morning, after I took a line I felt terrible. I was breathing fast and ideas were bad ideas were running through my head so fast. The night before a friend and I had made plans to hang out the next morning. He was going to pick me up the next morning and thank God he did. He showed up when I was freakin' the fuck out. He calmed me down and got me to my senses. I had thought I was gonna die. I decided then that I would stay clean for all of March from all drugs. It's been hard but deep down I know that it's the best choice for me. I don't have anything against molly or anyone who uses it. You just need to keep self control. In fact I plan to use it again when the month of March is up, but I'm gonna be smart about it this time. Also after March is over me and two close friends are gonna do acid. Both of my friends have done it before but it will be my first time. It'll kinda be a clebration for me staying clean. =) I wish all of you the best and have fun; just don't over do it. Do drugs and be safe, just don't let the drugs do you. (I also recommend not doing meth or anything like that, I have seen what it has done to people and familys. It's ugly and is something that no one should ever go through).

Serendip Visitor's picture

i love molly! but i know what

i love molly! but i know what you mean people can get crazy with out it. like he said kids dont over do it!

Serendip Visitor's picture

Was i spiked?

Last Saturday i went out with some friends, i drank quite alot before we went out and i was defiantly drunk, the first part of the night is pretty blurry as i have experienced before when i've drunk too much, so i'm not freak by that, it was the sudden change in the night, basically we went to the bar and I can kind of remember bits from there the next day just like when i've drunk to much in the passed and regretted it. just kind of not thinking and being on autopilot not really in control or thinking straight, but then I was suddenly in the street really aware, awake and like rushing on adrenaline and totally freaking out that people where chasing me and trying to shoot me, it was total nonsense, i was totally paranoid and freaking out, i was so terrified i stopped cars in the road begging for help or they were going to kill me, that i was being chased, i even bashed on a strangers door telling him to let me out the back door as the German government were out to kill me, and spiriting through the streets hiding in bushes from car headlights. i was totally irrational, but at the time i believed everything 100%. i know it's not just because i was just really drunk, it was like total opposite of alcohol my senses weren't dulled but working on over drive. If im drunk i do stupid stuff that i'd probably regret or not remember or like shit did that really happen, but with this i was suddenly very aware awake thinking crazy shit. i spoke to a friend who saw me when i'd somehow made it home she said i didn't sound drunk i was just freaking out that there were people outside trying to shoot me and thought i was joking until she realized i was totally terrified, my heart was racing in the morning still. Does anyone have any idea what would have tripped me out so bad, i've never taken hard drugs before and never experienced paranoia, i know i was really drunk but surely not just alcohol made me act like this. Any ideas what drug it could have been?

Serendip Visitor's picture

I tripped on MDMA twice.

I tripped on MDMA this year , the first time i did it was in a club. I have been smoking hashish for the past 7 years and used to smoke a lot a year back , as soon as woke i up in the past rolled a huge joint , smoked like 10 to 12 joints daily , but now as i am in a different country i smoke weed and not as many joints as before as it is quite expensive here , 1.4 grms of weed daily, I love to drink alcohol aswell with marijuana , i have experimented with cocain four times , i couldnt understand cocain for the first 3 times but the fourth time I felt invincible and felt like I am the "shitt" and no one can even come close to me , thats when i understood cocain , did a a little less then a gram at a short time with alcohol because i was curious and wanted to understand cocain and to know why it was so hyped up. My first trip on mdma was weird , i thought that my mind was strong enough and i could control myself nomatter what i did , but MDMA was something else , music sounded amazing , there was a weird bond among me and my friends who tripped with me , it wasnt their first time but it was mine , i did point 2 at the club, and had a feeling that i would go to sleep , more like a sleeping pill , i even asked my experienced friend who has experimented alot with drugs even lsd , he told me even if u try to sleep u wont be able to , youre just feeling this way , dont think to much and move , enjoy the music be positive i couldnt feel anything at first but then it started kicking in and my legs started to move,and thats when i started feeling better and wasnt feeling that i was going to pass out. at the club 3 random people came upto me at different times and asked me if i had any rizla bombs , and all three of them had dilated pupils and were smiling. I could tell the difference between the people who were on mdma and the people who were just drinking. A girl even tried talking to me and was smiling but i wasnt interested and was thinking to much because it was my first trip. i was comfortable after 15 minutes and started moving and enjoying , my friends kept on saying move and dance enjoy the music because it will make us happy if you move and i did and felt alot better , i had a very close friend with me to who was trying mdma for the first time too with me , the only thought that worried me was that i wanted him to enjoy too and i kept on feeling that he was not enjoying and was in anxiety , but later on when i saw him smile and comfortable i started enjoying more, when i came home we were still tripping , I had a third rizla bomb when i came home and now i was understanding mdma , istarted loving it , tripped alone in my room because the rest of my friends didnt pop the third rizla bomb ,i was listening to nine inch nails closer, and loved the song on mdma, drum and bass sounded amazing, even experimented with rock music like the band tool it sounded good but not as good as drum and bass . the second time i tried mdma was very very different , we tripped at home this time , the mdma looked a bit different too, it was white and had crystals unlike before which had a brownish tint on the crystals. This time the experience was insane , most of the time my eyes were closed , and we were listening to dark house , minimal , and tribal , I started using drugs for music , learnt how to play the drums when i was high on hash and even now i think it has helped me a lot in my creativity and i have a good reputation in the underground scene back in my country, I think hash has helped me develop my style in drumming, this time i had a feeling that i was connecting with the music too well , i could see patterns when my eyes were closed which were synced with the music perfectly and i kind of knew what was going to happen next in the music. I play the keyboard aswell and i could see the effects of the sounds in my brain , i know it sounds weird. it was a dark trip didnt have a very happy feel because two of my friends who were tripping hallucinated they saw the same thing , they thought that the lamp over there was a friend of ours without legs, and they could see my face change. I liked the trip and i have a different kind of emotional involvement with the trip eventhough it didnt have the happy feeling, it was like i was having sex with music , and was embracing it , whenever negative thoughts came in my mind, i would think that "listen to the music and embrace it, it means everything to you learn broaden your horizon, and i would think about my family and the positive things which were happening around me . After that experience I have started liking house music, before i used to listen to rock only as mentioned before im a drummer and wanted to only listen to rock so that i could specialise in one kind of genre, because i think specialisation is reached when someone devotes himself to it 100 percent , now I cant make a choice that what kind of music i want to make , i feel like making electronic music , but sometimes i conflict with myself and think that i was a hardcore metalhead but now i dont know what has happened to me , i listen to house a lot , i still love rock but now i think i wont be able to put in my full attention and effort in drumming like before, because my mind has broadened and my perceptions have changed , i love house too. I think broadening the mind is a good thing but you think a lot then, youre jack of all , master of none. and i am that kind of person who wants to be the best in something which i put my mind into.

Serendip Visitor's picture

You didn't trip.

MDMA isn't a hallucinogenic drug, it's an amphetimine. When you do MDMA you are being taken for a ride and have very little control of the feeling of the experience, it makes you feel one specific way almost every time.
When you graduate to mushrooms or LSD, you will notice that every experience you have is completely and totally unique, and very unpredictable. It is 100% up to you to control your experience by controlling your thoughts, you can either have an MDMA like experience or the worst experience of your life, it is totally up to you. MDMA leaves very, very little up to you, you know exactly what to expect every single time you take it(asuming you are getting pure MDMA, which is white) and there is very little you can do to change the "high". However, MDMA is a good introductory to hallucinogens, it is a somewhat similar experience(in terms of intensity, not characteristics) with very little possibility of having a bad experience. 99% of the people who do it (with proper doses) love it, it is called the love drug for a reason.

MDMA will not allow you to have an experience beneficial to your overall state of being, it is a drug meant for pure pleasure and nothing more. I would suggest you give mushrooms a try, the experience is not as enjoyable while you are doing it but your mind is working much more clearly and often you will have realizations about your life that will benefit you greatly. Also, the overall experience is much more intense than MDMA, and can be much more enjoyable if you are mentally able to handle the experience. Be careful though, if you are mentally unstable the experience could break your ego, and if you aren't ready to know your true self then it can be a very traumatic experience, especially if you are by yourself or with stupid people.

declan's picture

MDMA is a hallucinogenic

MDMA is a hallucinogenic drug, it comes under the entactogen sub-class of drugs, which has aspects of both stimulants and hallucinogens. And MDMA can give you just as many realizations and give you an experience beneficial to your overall state of being, just as acid or mushrooms could. I think you either have not legitamtely done MDMA or you had a certain experience and therefore assume that is the only kind of experience one can have on MDMA

Serendip Visitor's picture

jesus, thank you

these people are so confused.

great fan's picture

Please can anyone give me a

Please can anyone give me a full list of hallucinogens that exist or can I get a site that has a full list because I haven't been able to find it.

mariya's picture


Using drugs, and abusing them, can have plenty of effects on the user even after the drug use has stopped. Depending on the user, the type of the drug, and the severity of abuse, different drugs can produce different effects. Hallucinogenic drugs, however, alter a person’s perception of reality, and most likely will cause hallucinations and other alterations of their senses. Drugs that are classified as hallucinogens are: LSD, (lysergic acid diethylamide), psilocin, and mescaline. In these drugs, there are two aspects that classify them as hallucinogens. All of them have common side effects, which include distortion of sensory perception, and some other somatic and psychic effects. These drugs also display cross-tolerance, which means that a user of any hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used, and the shorter the time span is between the last usage.
Throughout history, hallucinogenic drugs have been used for a number of different reasons. They have been used in the medical field, as well as serving for religious purposes. In Native American ritual ceremonies, hallucinogenic drugs, such as mescaline, have been used.effects. These drugs also display cross-tolerance, which means that a user of any hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used, and the shorter the time span is between the last usage.
Throughout history, hallucinogenic drugs have been used for a number of different reasons. They have been used in the medical field, as well as serving for religious purposes. In Native American ritual ceremonies, hallucinogenic drugs, such as mescaline, have been used.

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There are many psychedelic

There are many psychedelic drugs out there. More than you can imagine. It is very hard to give you just one list of 'hallucinogens' based on your question. Each person is different, and even though a drug (for example, cannabis, or ecstacy) is not sold as a psychedelic or hallucinogen users may often experience similar or some effects that you would experience on drugs such as LSD.

If I was to assume you were simply talking about mind altering drugs that affect your 5 senses and whose primary action is to alter cognition and perception then I would suggest reading more on the following:

Datura (Highly not recommended!)
2CT- 2

Alot of these are research chemicals that many, even experienced users have never heard of. Please educate yourself before you take any of these. Alot of them are very different and more intense than LSD. Some lasting for 24hrs +.

Visit this link to find out a little more:
It's not the most trusted source out there, but it will give you an idea on how many different hallucinogens are available.

Stay Safe, and always have an experienced user of trusted person around you when trying something so mind altering.