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I saw the movie Paprika a few years ago, and I remember just mostly being really confused, so I would like to revisit this film and watch it for this class.

I think the House of Leaves would be interesting and unlike anything we've read before, but I'm also not sure how viable it would be for this class, as I have heard it can take a lot of time to piece through and decipher the book. I also liked the suggestion of Feed and Uglies, they both target a younger audience than anything we've read before, and offers a pretty different take on the intertwining of technology and humans than other works we've read. 

However I think out of the fiction books, as MissArcher2 suggested here, a novel by Octavia Butler, especially Fledgling, would be really interesting to read for this class.