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When I first read this question I was wondering- What is human nature? Without knowing this vital piece of information it is impossible to change anything. After asking myself this question I decided that in my opinion it doesn't matter what human nature is. All that matters is I know that changing the nature of a person is really hard, if not impossible. Having said that I would argue that changing "human nature" in general is impossible, unless of course there is no other choice. For example- if we assume that eating meat is a part of human nature I would argue that it is impossible to convince everyone to give up meat, but if the world some how ran out of meat, people would learn to change their nature. But again only if left with no other choice. 

If we had the choice should we change human nature? For this question I would argue the diversity of human nature. If we think about eating meat as an example of human nature then what about the vegetarians etc.? People differ in so many ways depending on likes or dislikes, culture or religion etc. that while one thing is a person's human nature it may not be another persons. In this case who gets to decide what human nature is or what to change?