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iwaldron's picture


Thank you for your suggestion and comment. I understand why it would be desirable to include the E site. However, we cannot accommodate a third site in the ribosome unless the ribosome is bigger than a standard piece of paper or we make all the simulation pieces smaller, and we have felt that these trade-offs were not favorable. We have not included the start codon because the methionine is removed from the hemoglobin polypeptide and we did not want to get into this complexity. We realize that both of these decisions are judgment calls. We have favored simplicity in this introductory activity, but we invite you to make changes as appropriate for your students.


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