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Perhaps the problem lies in imbalances in other chemicals in the chemical bath as well, such as how in schizophrenia treatment often consists of altering levels of multiple chemical agents including Dopamine's counterpart Serotonin. Perhaps treatment of one or with one chemical agent only temporarily relieves symptoms, since the change in one agent's presence is enough to affect a reaction so to speak, i.e. is able to replace one aspect of something that is missing from a the activity of CPG or is produced as a message in Corollary discharge, which until then had been absent or in insufficient quantities, thus, the missing or altered aspect produces results consistent with normal or recovering behavior. However, since one agent is not enough (since there are multiple agents in the system which all have been altered in some way by the disease) these symptoms of recovery can only extend so far before the insufficient presence (or over abundant presence) of other agents is taken into account and limits recovery. Also, perhaps the increase in dopamine itself has caused imbalances in the system which negatively affect the presence of other chemical agents, perhaps their activity is increased or decreased due to the presence of higher levels of dopamine (especially in the latter if the problem was more psychical ablation than chemical imbalance in the first place), so new problems arise with a similar effect. If we are proposing that Dopamine effects some CPG or corollary discharge unit, especially in the case of the latter, which reports on or to the activity of the effected area after all, where a change in chemical agents would most likely count in a change in the status quo, i.e. it may affect what the corollary discharge report about the effected area or even how the corollary discharge unit communicates to other parts nervous system (it could make it more fluid or more difficult or confuses or even inhibit communication)...or how other corollary discharge units respond to or receive and interpret, or don't receive and interpret signals as well. The addition of dopamine to this system thus may temporarily increase fluidity, correctness, occurrence of neuronal activity but ultimately proves to be not enough as those neural connections that need other chemical agents in the bath to communicate properly as well. I have admittedly never seen this movie...so I am interested in whether or not the patients in the movie received the same level of dopamine all the time or if the treatment stopped when they began to recover etc.