genetics

This overview reviews key concepts and learning activities to help students understand how genes influence our traits by molecular processes.  Topics covered include basic understanding of the important roles of proteins and DNA; DNA structure, function and replication; the molecular biology of how genes influence traits, including transcription and translation; the molecular biology of mutations; and genetic engineering. 

To help students understand the relevance of these molecular processes, the suggested learning activities link alleles of specific genes to human characteristics such as albinism, hemophilia, sickle cell anemia and muscular dystrophy. Suggested activities include analysis and discussion activities, hands-on laboratory and simulation activities, web-based simulations, and a vocabulary review game.

This activity is aligned with the Next Generation Science Standards. The attached files have the overview of key concepts, with descriptions of relevant learning activities and links to the activities. 

This analysis and discussion activity contains three "soap opera" episodes that help students to understand the principles of inheritance and the relevance of genetics to everyday life. In the first episode, students answer the probing questions of a skeptical father who wants to know how his baby could have albinism when neither he nor his wife have albinism.

The second episode, "Were the babies switched?", covers the concepts of codominance, incomplete dominance, and polygenic inheritance, and reinforces student understanding that the alleles of a gene give the instructions for making different versions of a protein.

In the third episode, students analyze sex-linked inheritance. Each episode can be used separately or with other episodes, depending on your teaching goals.

Part I summarizes key concepts in genetics. Part II presents common misconceptions. Part III recommends an integrated sequence of learning activities on the biological basis of genetics, plus seven human genetics learning activities. These learning activities develop student understanding of key concepts and counteract common misconceptions. Each of these recommended learning activities supports the Next Generation Science Standards (NGSS).

The resources include:

This hands-on, minds-on activity helps students to understand basic principles of genetics, including (1) how genotype influences phenotype via the effects of genes on protein structure and function and (2) how genes are transmitted from parents to offspring through the processes of meiosis and fertilization.

Students use model chromosomes to demonstrate how meiosis and fertilization are summarized in Punnett squares.

In the coin flip activity, students learn about the probabilistic nature of inheritance and Punnett square predictions.