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iwaldron's picture

Sickle cell trait

Submitted by iwaldron on Tue, 07/12/2016 - 2:47pm.

Your points are well-taken and are briefly described on page 10 of the Teacher Preparation Notes for this activity. In addition, these points are developed on page 6 of the Student Handout for "Genetics" (/sci_edu/waldron/#genetics).

My own inclination is that it is reasonable to postpone introducing these points until after the mitosis and meiosis and fertilization activities which are designed to precede the genetics activity. Please note that we do not describe the sickle cell allele as recessive, but only state that a heterozygous individual does not have sickle cell anemia, a statement which is correct since a heterozygous individual almost never experiences the symptoms of sickle cell anemia. However, I can understand if you and some other teachers feel that the points you have raised should be introduced from the beginning of the discussion of the sickle cell allele and welcome you to prepare a modified version of the Student Handout for your students.

Ingrid

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