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The Brain Magnified: Cerebellum

Degree of magnification
Human
Monkey
Cat
Rat
Frog
low
human cerebellum low power
monkey cerebellum low power
cat cerebellum low power
rat cerebellum low power
frog cerebellum low power
medium
human cerebellum med power
monkey cerebellum med power
cat cerebellum med power
rat cerebellum med power
frog cerebellum med power
high
human 20x- unavailable
monkey cerebellum high power
rat cerebellum high power
frog cerebellum high power



What do you notice about these pictures? Do they strike you as particularly similar or different? Perhaps with the exception of the frog cerebellum, you may notice that all of the photomicrographs look quite similar. At the low (4x) and medium (10x) magnification, we see that the organization of the cerebellum looks very similar across all the animals. In addition, even at the highest (20x) magnification, the neurons are apparently quite similar in both the human, monkey, cat, rat, and frog.

A main difference you may have seen is that there are a few larger cells in the monkey cerebellum under high power which are not as obvious in other animals. These are called Purkinje cells (whose axons constitute the sole output from the cerebral cortex). In general, "higher" mammals tend to have more pronounced, distinct Purkinje cells than "lower" mammals. Do you notice that in these pictures?




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I want to learn more about neurons!!!

Huh? Can we start over?