Cell and Molecular Neurobiology - Biology 304
GENERAL INFORMATION
Course instructor: Peter D. Brodfuehrer
Office: Room 210
Phone: 526-5095
e-mail: pbrodfue@brynmawr.edu
Class Locations:
Lecture: Tuesday and Thursday, 10 am -11:30 am
Biology 10
Labortory: Tuesday or Thursday, 2pm - 5pm
Biology 128
Textbook:
The Neuron: Cell and Molecular Biology
(second edition)
by Irwin B. Levitan and Leonard K. Kaczmarek.
additional readings will be put on reserve in Collier Library
Computer program: NeuroSim by BioSoft.
SYLLABUS
Material Covered in First Examination
Dates: Sept. 1 - Oct. 1
Textbook Chapers: 1 - 6
NeuroSim Tutorials
Topics
Cell biology of neurons
structure - function
axonal transport
Passive membrane properties of neurons
resistance
capacitance
current flow
Ionic basis of the action potential
Hodgkin and Huxley
voltage clamp
patch clamp
Ion channels - structure, function and diversity
Material Covered in Second Examination
Dates: Oct. 6 - Dec.8
Textbook Chapers: 7 - 12
NeuroSim Tutorials
Topics
Synaptic Transmission - Intercellular Communication
gap junctions
chemical synapse; stucture and function
G-proteins and second messengers
neuromodulation
neurotransmitters
synpatic integration
Textbook Chapers: 17 and 18
NeuroSim Tutorials
Topics
Neural Networks and Behavior
Learning and Memory
GRADING POLICY
Exam I (take home)
20%
Exam II (take home; due the last day of exams)
25%
Laboratory Report
(written and oral presentation)
20%
NeuroSim Assignments/Projects (3)
30%
Class Participation
5%